The Rdata containing GSEA results from this Rmd are used in OGlcNAc_early_embryo_Formichetti2023/Btgh_injected_blastocysts_SMARTSeq/src/Rmd/GSEA_morulae_blasto_comparison.Rmd to make the combined GSEA plot including morulae and blastocysts shown in paper figure.

1 Gene Set Enrichment Test

active vs dead - Biological Process GO
ID Description setSize enrichmentScore NES pvalue p.adjust qvalues rank leading_edge core_enrichment
GO:0008299 GO:0008299 isoprenoid biosynthetic process 17 0.8548257 2.233459 0.0000018 0.0082864 0.0080096 124 tags=35%, list=1%, signal=35% Fdft1/Fdps/Hmgcs1/Mvd/Lss/Hmgcr
GO:0001944 GO:0001944 vasculature development 356 -0.3816501 -1.570555 0.0000204 0.0238948 0.0230966 2380 tags=31%, list=22%, signal=25% Tgfbr1/Tjp1/Egfl7/Rasa1/Errfi1/Klf4/Fzd5/Bmpr1a/Add1/Fmnl3/Spry2/Mia3/Smad5/Plcd1/Sufu/Col4a2/Paxip1/Hs6st1/Jun/Tbx3/Nedd4/Ddah1/Grn/Nfe2l2/Jmjd8/Plxnd1/Pten/Sema4a/Ptk7/B9d1/Notch2/Hif1a/Eng/Lrp5/Zfp950/Adtrp/Klf5/Mib1/Rnf213/Mfge8/Dicer1/Brpf1/Wars/Rapgef2/Hmox1/Stim1/Hectd1/Pml/Pdpn/Qk/Ago1/Angpt2/Otulin/Rxra/Pik3c2a/Tdgf1/Sos1/Arid2/Pdgfa/Pecam1/Tnfrsf12a/Cx3cl1/Kat6a/Wars2/Ago2/Mapk14/Hhex/Psen1/Amotl2/Htatip2/Hdac5/Tbx20/Runx1/Cib1/Lrp2/Ccn1/Pkd1/Mtdh/Xbp1/Smad7/Rtn4/Cd59a/Ccn2/Smarca2/Angptl4/Itgav/Dab2ip/Cdx2/Sirt1/Ncl/Zbtb14/Cemip2/Gna13/Rbpj/Jup/Plpp3/Folr1/Med1/Lgals8/Amot/Ric8a/Glmn/Hk2/Btg1/Ankrd17/Pdcd4/Hmga2/Apoe/Enpep/Gpx1/Pdcd6
GO:0016126 GO:0016126 sterol biosynthetic process 42 0.6377318 2.047479 0.0000845 0.0472729 0.0456938 124 tags=19%, list=1%, signal=19% Fdft1/Fdps/Sqle/Msmo1/Hmgcs1/Mvd/Lss/Hmgcr
GO:0031061 GO:0031061 negative regulation of histone methylation 22 -0.7632241 -2.050041 0.0001027 0.0472729 0.0456938 523 tags=23%, list=5%, signal=22% Sirt1/Wdr5/Dnmt3b/Mtf2/Mllt6
active vs dead - Molecular Function GO
ID Description setSize enrichmentScore NES pvalue p.adjust qvalues rank leading_edge core_enrichment
GO:0003735 GO:0003735 structural constituent of ribosome 158 -0.5406364 -2.040804 0.0000000 0.0000105 0.0000097 1881 tags=37%, list=18%, signal=31% Uba52/Rps20/Rpl30/Rpl19/Rps13/Mrps5/Rps19/Rpl31/Rpl21/Rpl41/Mrps35/Mrps17/Mrpl3/Rps12/Mrpl19/Rps23/Mrps11/Rpl37a/Mrpl47/Mrpl21/Rps18/Rpl12/Rps10/Rpl15/Rps5/Mrps31/Rplp1/Mrps30/Fau/Mrpl41/Mrps21/Rpl18/Rps4x/Rpl24/Rpl18a/Rpl10a/Rpl10l/Rpl7/Rps16/Rpl10/Mrpl30/Rpl22l1/Rpl13/Mrps15/Mrpl35/Mrpl18/Rps9/Mrps14/Mrps18a/Rps6/Mrpl16/Rpl5/Rps27a/Mrpl27/Srbd1/Mrpl1/Mrps18c/Mrpl54/Rpl3
GO:0015453 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 40 -0.7050142 -2.114842 0.0000023 0.0006278 0.0005832 720 tags=32%, list=7%, signal=30% Ndufb7/COX1/Uqcrq/Ndufs7/ND6/Cox4i1/Ndufc2/ND5/Ndufb8/Cox7b/ND4/ND2/Uqcrfs1
GO:0003954 GO:0003954 NADH dehydrogenase activity 22 -0.7748929 -2.064641 0.0000120 0.0024564 0.0022818 720 tags=41%, list=7%, signal=38% Ndufb7/Ndufs7/ND6/Ndufc2/ND5/Ndufb8/ND4/Ndufa9/ND2
GO:0019843 GO:0019843 rRNA binding 72 -0.5497919 -1.857403 0.0001053 0.0112175 0.0104204 1817 tags=36%, list=17%, signal=30% Rpl19/Rps13/Mrps17/Npm1/Mrps11/Rpl37a/Mrps27/Rps18/Rpl12/Rps5/Utp25/Cavin1/Nop53/Rps4x/Rpl7/Mrpl18/Ncl/Rps9/Mrps18a/Mrpl16/Rpl5/Taco1/Rpf1/Mrps18c/Rpl3/Eef2
GO:0009055 GO:0009055 electron transfer activity 54 -0.5884181 -1.884592 0.0001362 0.0123595 0.0114812 720 tags=24%, list=7%, signal=23% Ndufb7/COX1/Uqcrq/Ndufs7/ND6/Cox4i1/Ndufc2/ND5/Ndufb8/Cox7b/ND4/ND2/Uqcrfs1
active vs dead - Cellular Component GO
ID Description setSize enrichmentScore NES pvalue p.adjust qvalues rank leading_edge core_enrichment
GO:0005840 GO:0005840 ribosome 214 -0.5000608 -1.945704 0.0000000 0.0000146 0.0000131 1886 tags=34%, list=18%, signal=29% Mrps33/Uba52/Rps20/Rpl30/Rpl19/Rps13/Mrps5/Rps19/Rpl31/Rpl21/Rpl41/Mrps35/Mrps17/Mrpl3/Npm1/Rps12/Mrpl19/Rps23/Mrps11/Eif2ak4/Ddx3x/Rpl37a/Mrpl47/Btf3/Mrps27/Mrpl21/Rps18/Rps18-ps5/Rpl12/Rps10/Rpl15/Rps5/Mrps31/Rplp1/Mrps30/Fau/Dmd/Mrpl41/Mrps21/Rpl18/Rps4x/Rpl24/Rpl18a/Rpl10a/Rpl10l/Rpl7/Abcf1/Rps16/Rpl10/Mrpl30/Rpl22l1/Aurkaip1/Rpl13/Rack1/Mrps15/Mrpl35/Mrpl18/Rps9/Mrps28/Mrps14/Mrps18a/Rps6/Eif2d/Mrpl16/Rpl5/Rps27a/Mrpl27/Mcts1/Mrpl1/Mrps18c/Mrpl54/Rpl3/Eef2
GO:0070469 GO:0070469 respirasome 81 -0.5301676 -1.818783 0.0000988 0.0118991 0.0106736 973 tags=26%, list=9%, signal=24% Coa6/Ndufc1/AA467197/Cox6b1/Ndufb7/COX1/Ndufb11b/Ndufa4/Uqcrq/Cox7b2/Ndufs7/ND6/Cox4i1/Ndufc2/ND5/Ndufb8/Cox7b/ND4/Ndufa9/ND2/Uqcrfs1
GO:0005615 GO:0005615 extracellular space 351 -0.3700184 -1.515164 0.0002055 0.0206223 0.0184984 2569 tags=34%, list=24%, signal=27% C1qtnf12/Gfra1/Lif/Car4/Tnfsf13b/Prl3b1/Amn/Fbln1/Atp6ap2/Capg/Acpp/Raet1e/Egfl7/Tsku/Nrg4/Pdia3/Cd1d1/Lipg/Clic1/Gfer/Bag6/Col4a2/Nppc/Alpl/Grn/Plaa/Bmp8b/Tctn1/Ahnak/Ctsz/Dkkl1/Col9a2/Sema4a/Acy1/Mertk/Plbd1/Gas6/Serpinb6a/Erfe/Raet1a/Eng/Tcn2/Rap2b/Ctsc/Npc2/Vpreb3/Ctsl/Smoc1/Ckb/Mfge8/Cxadr/Col7a1/Smpd1/Il17b/Dicer1/Serpine2/Gsn/Sema4b/Fam3a/Ctsb/Angpt2/Tpsg1/Hspa4/Tdgf1/Pdgfa/Mif/Pecam1/Agrn/Tacstd2/H2-D1/Flrt1/Cpxm1/Cx3cl1/Prtn3/Wfdc15a/Ago2/Fau/Hdgf/Pebp1/Soga1/Cilp2/Zan/Apom/Lama5/Pzp/Hmgb2/Mtcl1/Lrp2/Gpc4/Pkd1/Creg1/Cd59a/Ccn2/Angptl4/Rab11a/Fuca2/Ppt1/Lman2/Gdf3/Ren1/Cst3/Agrp/Fgf3/S100a10/Cpn1/Selenos/Cpm/B2m/Smpdl3a/Pnliprp2/Cstb/Gc/Fabp5/Sfrp1/Cd63/Lamp2/Apoc1/Fabp3/Apoe
GO:0098798 GO:0098798 mitochondrial protein-containing complex 241 -0.3933146 -1.546418 0.0004826 0.0290528 0.0260606 1726 tags=31%, list=16%, signal=26% Mrps9/Mrpl23/Agk/CYTB/Ndufb2/Mrps2/Mrpl37/Pdk2/Bckdha/Mtx3/Timm13/Phb2/Bckdhb/Mtx1/Mrps5/Ndufb3/Romo1/Mrps35/Mrps17/Mrpl3/Mrpl19/Mrps11/Dmac1/Mrpl47/Apoo/Mrps27/Ndufa1/Mrpl21/Uqcrb/Atp5j2/Mtx2/Mrps31/Mrps30/Grpel1/Ndufc1/AA467197/Mrpl41/Mrps21/Ndufb7/Timm9/COX1/Atp5d/Ndufb11b/Mrpl30/Atp5pb/Atp5g3/Ndufa4/Uqcrq/Mrps15/Mrpl35/Mrpl18/Ndufs7/Mrps28/Hsd17b10/Mrps14/Mrps18a/Cox4i1/Mrpl16/Timm10/Dnajc19/Ndufc2/ND5/Ndufb8/Ppif/Mrpl27/ND4/Mrpl1/Ndufa9/Chchd10/ND2/Mrps18c/Mrpl54/Apool/Uqcrfs1
GO:0072686 GO:0072686 mitotic spindle 132 0.4237246 1.614052 0.0006326 0.0346192 0.0310538 1792 tags=31%, list=17%, signal=26% Ska1/Cdc6/Tubg1/Rangap1/Hsf1/Map4/Cdc7/Prc1/Haus4/Sirt2/Mad1l1/Aaas/Ska3/Cep170/Tacc3/Espl1/Ngrn/Aurka/Yeats2/Nudc/Nudcd2/Rcc2/Cdk1/Tpx2/Cttn/Kif23/Tada3/Mapre1/Kifc1/Katnbl1/Nusap1/Kif22/Kif18b/Spout1/Wapl/Togaram1/Racgap1/Mad2l1/Nin/Nup62/Spag5
active vs ctrl - Biological Process GO
ID Description setSize enrichmentScore NES pvalue p.adjust qvalues rank leading_edge core_enrichment
GO:0030036 GO:0030036 actin cytoskeleton organization 410 -0.4331960 -1.814949 0.0000000 0.0000027 0.0000024 1592 tags=26%, list=15%, signal=23% Mical3/Myo19/Sdc4/Mob2/Elmo3/Add3/Mical1/Ctsl/Mprip/Arfip2/Epha1/Strip1/Pafah1b1/Taok2/Slc9a3r1/Iqgap1/Twf1/Kank2/Arpc2/Hdac2/Add1/Vasp/Pdlim5/Sfrp1/Mfn2/Arhgdib/Pacsin2/Amotl2/Mphosph8/Flnb/Arhgef5/Smad3/Map3k1/Pycard/Sdad1/Pdgfra/Enah/Dmd/Arhgef2/Mkln1/Epb41l5/Specc1l/Nisch/Pfn2/Pecam1/Ehbp1/Notch2/Tacstd2/S100a10/Cdc42ep2/Ctnna1/Ooep/Pstpip1/Emp2/Fscn1/Cdc42/Tmsb10/Actr2/Epb41l1/Coro1b/Tpm4/Cnn2/Nck2/Ccn2/Pdgfa/Carmil1/Amot/Inppl1/Krt8/Cap1/Mtpn/Ppargc1b/Whamm/Cd2ap/Capza2/Zyx/Pik3r1/Pick1/Ezr/Capg/Msrb2/Plec/Arpc5/Pdlim7/Khdc3/Gmfb/Pdlim1/Tpm1/Calr/Swap70/Cgnl1/Cdh1/Braf/Actg1/Cxadr/Hsp90b1/Rnd2/Csrp1/Arf1/Rnd3/F11r/Actr3/Rdx/Myo5b/Epb41/Arpc1b/Wdr1/Marcks
GO:0030029 GO:0030029 actin filament-based process 443 -0.4214052 -1.782910 0.0000000 0.0000027 0.0000024 1592 tags=26%, list=15%, signal=23% Mical3/Myo19/Sdc4/Mob2/Atp1a1/Elmo3/Add3/Mical1/Ctsl/Mprip/Arfip2/Epha1/Strip1/Pafah1b1/Taok2/Slc9a3r1/Iqgap1/Twf1/Kank2/Mylk2/Arpc2/Hdac2/Add1/Vasp/Pdlim5/Sfrp1/Mfn2/Arhgdib/Pacsin2/Amotl2/Dsg2/Mphosph8/Flnb/Arhgef5/Smad3/Map3k1/Pycard/Sdad1/Pdgfra/Enah/Dmd/Arhgef2/Mkln1/Epb41l5/Specc1l/Nisch/Pfn2/Pecam1/Ehbp1/Notch2/Tacstd2/S100a10/Cdc42ep2/Fnbp1l/Ctnna1/Ooep/Pstpip1/Emp2/Fscn1/Cdc42/Tmsb10/Actr2/Epb41l1/Coro1b/Tpm4/Cnn2/Nck2/Ccn2/Pdgfa/Carmil1/Amot/Inppl1/Krt8/Cap1/Mtpn/Ppargc1b/Whamm/Cd2ap/Capza2/Srgap2/Zyx/Pik3r1/Pick1/Ezr/Capg/Msrb2/Plec/Arpc5/Pdlim7/Khdc3/Gmfb/Pdlim1/Tpm1/Calr/Swap70/Cgnl1/Cdh1/Braf/Actg1/Cxadr/Hsp90b1/Rnd2/Csrp1/Arf1/Rnd3/F11r/Actr3/Rdx/Myo5b/Epb41/Arpc1b/Wdr1/Marcks
GO:0043648 GO:0043648 dicarboxylic acid metabolic process 59 -0.6922745 -2.284769 0.0000000 0.0000079 0.0000070 1678 tags=41%, list=16%, signal=34% Nit2/Me1/Ogdh/Suclg1/Sdha/Mdh1/Ogdhl/Oat/Ass1/Got2/Sdhb/Dld/Dlst/Grhpr/Got1/Sucla2/Idh3g/Kyat3/Fh1/Glud1/Idh3a/Adss/Idh1/Cs
GO:0034330 GO:0034330 cell junction organization 346 -0.4242520 -1.742468 0.0000000 0.0000222 0.0000197 2453 tags=39%, list=23%, signal=31% Actb/Pkp4/Ptprs/Pard6a/Rhoa/Afdn/Rheb/Cadm1/L1cam/Pak2/Dlc1/Sema4d/Grhl1/Plxnd1/Grid2/Mtss1/Sdf4/Wasf2/Pard3/Rab17/Rhod/Jup/Myh10/Hipk1/Cttn/Flrt1/Opa1/Fgfr2/Kalrn/Dab2ip/Lamc1/Afg3l2/Mapt/Actn2/Arhgef7/Tgfbr1/Septin11/Hnrnpk/Septin7/Dnm1l/Lrp8/Nrg1/Actn4/Hnf4a/Plxnb2/Pard6b/Flot1/Dsp/Ptpra/Apoe/Sdc4/Col4a1/Mpp7/Peak1/Insr/Tns1/Ocln/Caprin1/Slc25a46/Pafah1b1/Sez6l2/Epha4/Psen1/Erbb2/Taok2/Fzd5/Iqgap1/Numbl/Clstn1/Mapk14/Chmp2b/Dusp3/Add1/Patj/Rapgef2/Tanc1/Pdlim5/Mfn2/Dsg2/Prtn3/Etv5/Smad3/Setd5/Atp2b2/Vps35/Itgav/Epb41l5/Sparc/Fn1/Specc1l/Pfn2/Pecam1/Chchd10/Dgkz/Xlr3b/S100a10/Slc9a6/Ctnna1/Tuba1a/Fscn1/Cdc42/Actr2/Obsl1/Pten/Whamm/Pik3r1/Ywhaz/Pick1/Lsr/Pgrmc1/Efnb2/Plec/Vcl/Cldn6/Ptpn11/Apbb1/Cdh1/Cgn/Perp/Gja1/Actg1/Cxadr/Cldn4/Dag1/Nedd4/Vcp/Arf1/F11r/Actr3/Rdx/Mesd/Myo5b/Tjp2/Wdr1/Marcks
GO:0040017 GO:0040017 positive regulation of locomotion 289 -0.4293722 -1.747731 0.0000004 0.0002864 0.0002537 2077 tags=32%, list=19%, signal=26% Prkd2/Dab2ip/Bsg/Lgals3/Capn7/Jcad/Cd99l2/Cavin1/Atp5b/Tgfbr1/Gpi1/Dnm1l/Fer/Bcar1/Dapk2/Actn4/Tert/Hif1a/Mpzl1/Selenok/Insr/Epha1/Fam83h/Plpp3/Grb7/Dab2/Tiam1/Iqgap1/S100a11/Stat3/Arpc2/Plaa/Sema5b/Akirin1/Rapgef2/Cpne3/Smad3/Pycard/Vps35/Tirap/Pdgfra/Itgav/Arhgef2/Epb41l5/Sparc/Fn1/Elp3/Pecam1/Abcc1/Ccn1/Fbln1/Ppp3ca/Lyn/Ago2/P2rx4/Map2k3/Hdac4/Pdgfa/Carmil1/Amot/Tmem102/Mia3/Itga6/Sema4b/Arhgap5/Rras2/Pik3r1/Ptp4a1/Lamb1/Atp5a1/Hspa5/Calr/Gata3/Swap70/Stx3/Hmox1/Acvr1b/Actg1/Ptp4a1/Aldoa/Cldn4/Cd151/Epcam/Rtn4/Xbp1/Nfe2l2/Pdcd6/Rab11a/Actr3/Akap12/Rdx/Plet1
GO:2000147 GO:2000147 positive regulation of cell motility 284 -0.4254377 -1.733560 0.0000006 0.0003723 0.0003297 2077 tags=32%, list=19%, signal=26% Prkd2/Dab2ip/Bsg/Lgals3/Capn7/Jcad/Cd99l2/Cavin1/Atp5b/Tgfbr1/Gpi1/Dnm1l/Fer/Bcar1/Dapk2/Actn4/Tert/Hif1a/Mpzl1/Selenok/Insr/Epha1/Fam83h/Plpp3/Grb7/Dab2/Tiam1/Iqgap1/S100a11/Stat3/Arpc2/Plaa/Sema5b/Akirin1/Rapgef2/Cpne3/Smad3/Pycard/Tirap/Pdgfra/Itgav/Arhgef2/Epb41l5/Sparc/Fn1/Elp3/Pecam1/Abcc1/Ccn1/Fbln1/Ppp3ca/Lyn/Ago2/P2rx4/Map2k3/Hdac4/Pdgfa/Carmil1/Amot/Tmem102/Mia3/Itga6/Sema4b/Arhgap5/Rras2/Pik3r1/Ptp4a1/Lamb1/Atp5a1/Hspa5/Calr/Gata3/Swap70/Hmox1/Acvr1b/Actg1/Ptp4a1/Aldoa/Cldn4/Cd151/Epcam/Rtn4/Xbp1/Nfe2l2/Pdcd6/Rab11a/Actr3/Akap12/Rdx/Plet1
GO:0006091 GO:0006091 generation of precursor metabolites and energy 289 -0.4237746 -1.724946 0.0000008 0.0004365 0.0003866 2026 tags=33%, list=19%, signal=27% 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
GO:0022603 GO:0022603 regulation of anatomical structure morphogenesis 493 -0.3666279 -1.561551 0.0000012 0.0004963 0.0004396 2604 tags=35%, list=24%, signal=28% Arap1/Rhoa/Lst1/Afdn/Mcu/Hgs/Diaph1/L1cam/Pak2/Ulk1/Triobp/Ddah1/Spry1/Dlc1/Sema4d/P4hb/Plxnd1/Tmbim1/Gna12/Fmnl3/Myl12b/Bmpr1a/Zdhhc6/Cdc42ep5/Tcf4/Sirt1/Rhod/Jup/Myh10/Cd59a/Med12/Mff/Arhgdia/Opa1/Fgfr2/Bcl9l/Prkd2/Kalrn/Syne3/Dab2ip/Lgals3/Jak1/Jcad/Phb2/Brwd3/Mapt/Gtf2i/Myh9/Hnrnpk/Msn/Dnm1l/Ankrd27/Eng/Lrp8/Bcar1/Nrg1/Trak1/Wars2/Actn4/Pkn1/Hnf4a/Tert/Plxnb2/Reck/Hif1a/Fxn/Pak4/Apoe/Myo19/Cux1/Spg20/Caprin1/Epha1/Strip1/Pafah1b1/Epha4/Psen1/Brca1/Taok2/Pml/Dab2/Tiam1/Pias2/Slc9a3r1/Numbl/Stat3/Arpc2/Runx1/Map6/Myl12a/Pkm/Net1/Plaa/Add1/Sema5b/Rapgef2/Col4a2/Pdlim5/Slc23a2/Sfrp1/Mfn2/Etv5/Vps35/Htatip2/Pdgfra/Tgif1/Mkln1/Sparc/Myo10/Fn1/Otx2/Hhex/Tacstd2/Xlr3b/S100a10/Fbln1/Cdc42ep2/Ppp3ca/Ago2/Jmjd8/Emp2/Cdc42/Actr2/Mul1/Gna13/Cdc42se2/Obsl1/Frs2/Trak2/Coro1b/Wars/Pdgfa/Carmil1/Amot/Dnmbp/Pten/Rbpj/Sema4b/Anxa7/Efnb2/Ezr/Hmga2/Mief1/Tpm1/Btg1/Calr/Gata3/Skil/Cdx2/Hmox1/Cdh1/Eif2b2/Braf/Gja1/Aldoa/Cldn4/Dag1/Rnd2/Rtn4/Xbp1/Nfe2l2/Pdcd6/Nedd4/Rab11a/Rnd3/F11r/Actr3/Rdx/Myo5b/Epb41/Wdr1/Hk2/Marcks
GO:0006099 GO:0006099 tricarboxylic acid cycle 28 -0.7593360 -2.118078 0.0000033 0.0009559 0.0008466 1883 tags=64%, list=18%, signal=53% Sdhc/Dlat/Aco2/Ogdh/Suclg1/Sdha/Mdh1/Ogdhl/Pdha1/Sdhb/Dlst/Sucla2/Idh3g/Fh1/Idh3a/Idh1/Aco1/Cs
GO:0061061 GO:0061061 muscle structure development 324 -0.3965225 -1.624576 0.0000075 0.0017602 0.0015590 2329 tags=31%, list=22%, signal=25% Asf1a/Prickle1/Bmpr1a/Chuk/Cacybp/Sirt1/Prr14/Myh10/Bin1/Zfhx3/Zfp418/Fgfr2/Ptbp1/Bnip2/Slc9a1/Bcl9l/Creb1/Afg3l2/Myh9/Actn2/Tgfbr1/Kdm1a/Chd2/Eng/G6pdx/Nrg1/Qk/AW551984/Actn4/Smarca2/Meg3/Flot1/Dsp/Lama5/Sdc1/Popdc3/Usp2/Il4ra/Hdac3/Msc/Mapk14/Mylk2/Gsc/Pitx1/Bin3/Hdac2/Akirin1/Tanc1/Smyd1/Pdlim5/Sra1/Mfn2/Ehd1/Ptcd2/Flnb/Smad3/Tbx20/Med1/Pdgfra/Epas1/Foxh1/Rcan1/Glmn/Dmd/Piezo1/Cops2/Ppp3ca/Ube4b/Lmna/Gpx1/Frs2/H1f5/Hdac4/Gdf3/Cd164/Krt8/Rbpj/Lrp2/Pik3r1/Eif5a/Efnb2/Plec/Id2/Erbb3/Pdlim7/Pdlim1/Tpm1/Btg1/Skil/Gja1/Actg1/Cxadr/Ybx3/Dag1/Xbp1/Csrp1/Slc25a4/Pdcd4/Ankrd17/Wdr1/Kdm6b
GO:0031589 GO:0031589 cell-substrate adhesion 185 -0.4531911 -1.755951 0.0000079 0.0017602 0.0015590 2678 tags=40%, list=25%, signal=30% Lims1/Kank1/Nid1/Rhoa/Nexmif/L1cam/Triobp/Dlc1/Lgals1/P4hb/Plau/Rhod/Jup/Cttn/Gas6/Vamp3/Col26a1/Tyro3/Akip1/Lamc1/Actn2/Fer/Bcar1/Actn4/Itgb5/B4galt1/Ptpra/Lama5/Sdc4/Cdk6/Peak1/Epha1/Taok2/Dab2/Tiam1/Iqgap1/Smoc1/Arpc2/Adam15/Net1/Dusp3/Sfrp1/Smad3/Dmd/Itgav/Mkln1/Epb41l5/Fn1/Hsd17b12/Pecam1/Tacstd2/S100a10/Ccn1/Fbln1/Rab1a/Emp2/Cdc42/Ccn2/Carmil1/Itga6/Pten/Whamm/Srgap2/Zyx/Pik3r1/Vcl/Lamb1/Calr/Ptpn11/Braf/Actg1/Dag1/Marcks/Plet1
GO:0030155 GO:0030155 regulation of cell adhesion 354 -0.3772208 -1.556802 0.0000161 0.0034253 0.0030339 2712 tags=40%, list=25%, signal=31% Peli1/Hspb1/Hsp90aa1/Lims1/Kank1/Rc3h1/Nid1/Epb41l4b/Kng1/Rhoa/Casp3/Afdn/Lama3/Nexmif/Pkd1/L1cam/Zdhhc21/Triobp/Vav1/Dlc1/Sema4d/Lgals1/P4hb/Plxnd1/Il12rb1/Zbtb7b/H2-Ab1/Vsir/Gpam/Plau/Bcl10/Rhod/Dpp4/Jup/Cd59a/Jam2/Col26a1/Zfhx3/Prkd2/Slc7a1/Lgals3/Jak1/Lgals8/Gsn/Dusp10/Gstp1/Atp5b/Cbfb/Bcar1/Nrg1/Actn4/Plxnb2/Socs6/Flot1/Ephb6/H2-DMb1/Ptpra/Lama5/Sdc4/H2-DMb2/Cdk6/Selenok/Peak1/Spg7/Il4ra/Epha1/Cd55/Pnp/Epha4/Erbb2/Plpp3/Pag1/Taok2/C2cd4a/Nkap/Pml/Dab2/H2-Oa/Iqgap1/Smoc1/Blm/Mapk14/Arpc2/Adam15/Runx1/Net1/Dusp3/Gtpbp4/Smad3/Pycard/Glmn/Dmd/Itgav/Epb41l5/Myo10/Fn1/Specc1l/Hsd17b12/Ass1/Piezo1/Prdx2/Tacstd2/S100a10/Ccn1/Fbln1/Spint2/Ppp3ca/Lyn/Emp2/Socs1/Cdc42/Tfe3/Nck2/Carmil1/Tmem102/Cyth3/Mia3/Itga6/Pten/Rbpj/Ppp1cb/Pik3r1/Efnb2/Vcl/Erbb3/Tpm1/Lamb1/Calr/Gata3/Swap70/Stx3/Ptpn11/Cdh1/Braf/Actg1/Dag1/Epcam/Xbp1/F11r/Rdx/Ndfip1/Plet1
GO:0000904 GO:0000904 cell morphogenesis involved in differentiation 402 -0.3658746 -1.530942 0.0000233 0.0042017 0.0037215 2681 tags=35%, list=25%, signal=27% Hsp90aa1/Mfsd2a/Lims1/Kank1/Actb/Ptprs/Wdr36/Rhoa/Afdn/Lama3/Cdh23/L1cam/Pak2/Ulk1/Triobp/Spg11/Ythdf1/Pip5k1c/Sema4d/P4hb/Plxnd1/C1galt1c1/Pard3/Usp9x/St14/Zfp385a/Myh10/Cttn/Vamp3/Opa1/Fgfr2/Tyro3/Kalrn/Bsg/Akip1/Lamc1/Creb1/Afg3l2/Mapt/Myh9/Rabl2/Septin7/Cfap418/Dnm1l/Ankrd27/Fer/Lrp8/Bcar1/Nrg1/Trak1/Actn4/Lats2/Plxnb2/Fxn/Flot1/Ephb6/Lama5/Apoe/Cux1/Peak1/Spg20/Caprin1/Epha1/Slc25a46/Pafah1b1/Epha4/Psen1/Erbb2/Taok2/Dab2/Tiam1/Pias2/Slc9a3r1/Numbl/Rbfox2/Arpc2/Map6/Raph1/Net1/Sema5b/Clic4/Rapgef2/Vasp/Pdlim5/Sfrp1/Mfn2/Prtg/Flnb/Map3k1/Atp2b2/Enah/Itgav/Epb41l5/Fn1/Otx2/Spr/Pecam1/Tacstd2/Xlr3b/S100a10/Slc9a6/Fbln1/Spint2/Ppp3ca/Rab1a/Cdc42/Actr2/Tet1/Obsl1/Trak2/Carmil1/Krt8/Pten/Sema4b/Tsku/Srgap2/Lrp2/Smn1/Efnb2/Vcl/Id2/Lamb1/Calr/Gata3/Skil/Ptpn11/Apbb1/Cdh1/Eif2b2/Braf/Cgn/Dag1/Rnd2/Rtn4/Nedd4/Rab11a/Actr3/Myo5b/Wdr1/Marcks/Igf2bp1
GO:1904377 GO:1904377 positive regulation of protein localization to cell periphery 43 -0.6506518 -1.989723 0.0000385 0.0060073 0.0053208 319 tags=19%, list=3%, signal=18% Pgrmc1/Ezr/Stx3/Rab11a/Actr3/Myo5b/Epb41/Sqstm1
GO:0001568 GO:0001568 blood vessel development 337 -0.3747191 -1.536000 0.0000472 0.0069549 0.0061601 2320 tags=34%, list=22%, signal=27% Wasf2/Prickle1/Bmpr1a/Plau/Tcf4/Llgl2/Naa15/Sirt1/Jup/Myh10/Cd59a/Spint1/Rnf213/Fgfr2/Prkd2/Dab2ip/Bsg/Lgals3/Jak1/Jcad/Tab1/Gtf2i/Myh9/Atp5b/Tgfbr1/Eng/Egfl7/Qk/Zbtb14/Wars2/Anxa2/Aimp1/Tert/Reck/B4galt1/Hif1a/Pak4/Apoe/Col4a1/Cemip2/Arid2/Foxm1/Ggnbp2/Epha1/Psen1/Brca1/Plpp3/Chm/Pml/Fzd5/Mapk14/Stat3/Adam15/Runx1/Pkm/Add1/Clic4/Hs6st1/Rapgef2/Col4a2/Amotl2/Acvr2b/Tbx20/Plcd1/Htatip2/Med1/Pdgfra/Ppp3r1/Epas1/Foxh1/Glmn/Itgav/Hectd1/Sparc/Fn1/Hhex/Pecam1/Notch2/Becn1/Ccn1/Ago2/Jmjd8/Emp2/Gpx1/Cdc42/Gna13/Mfge8/Wars/Ccn2/Pdgfa/Amot/Mia3/Pten/Rbpj/Sgpl1/Lrp2/Ywhaz/Efnb2/Angptl4/Hmga2/Btg1/Cdx2/Hmox1/Gja1/Ncl/Actg1/Rtn4/Xbp1/Nfe2l2/Pdcd6/Nedd4/Ankrd17/Hk2/Enpep
GO:0030855 GO:0030855 epithelial cell differentiation 285 -0.3900798 -1.590228 0.0000485 0.0069549 0.0061601 1723 tags=25%, list=16%, signal=21% Lats2/Hnf4a/B9d1/B4galt1/Hif1a/Dsp/Slc4a5/Cux1/Ugcg/Errfi1/Cdk6/Pafah1b1/Ncor2/Yipf6/Kdm2a/Dab2/Slc9a3r1/Hdac2/Add1/Kdf1/Clic4/Rapgef2/Psap/Flnb/Acvr2b/Smad3/Map3k1/Rap2c/Irf6/Atp2b2/Med1/Ppp3r1/Dmd/Epb41l5/Ercc3/Hhex/Pecam1/Notch2/Macroh2a1/Spint2/Bccip/Gpx1/Cdc42/Srsf6/Frs2/Gdf3/Asah1/Elf3/Rbpj/Ezr/Plec/Vcl/Msx2/Id2/Btg1/Gata3/Skil/Cdx2/Ampd2/Tagln2/Cdh1/Cgn/Gja1/Xbp1/Tfcp2l1/Intu/F11r/Rdx/Tjp2/Kdm6b
GO:0055065 GO:0055065 metal ion homeostasis 269 -0.3941052 -1.602369 0.0000496 0.0069549 0.0061601 1690 tags=28%, list=16%, signal=24% Steap3/Ankrd9/Hif1a/Fxn/Atp12a/Atp6v0a2/Slc35g1/Apoe/Abcb7/Atp1a1/Gna15/Selenok/Cd55/Abcb6/Psen1/Slc39a14/Atp13a1/Atp6v1a/Tmem64/Tpcn2/Pml/Letm1/Slc31a2/Cherp/Rmdn3/Clstn1/Atp7b/Slc39a7/Fbxl5/Chga/Asph/Atp2b1/Mfn2/Mcur1/Smad3/Atp2b2/Plcd1/Steap1/Pdgfra/Epas1/Dmd/Itgav/Ywhae/Comt/Tmbim6/Nubp1/Slc39a10/Oga/Lyn/Gnb1/P2rx4/Gna13/Calm2/Frrs1/Immt/Sco1/Anxa7/Fech/Tmco1/Eif5a/Got1/Wfs1/Aplp2/Swap70/Slc24a5/Hmox1/Ftl1/Gja1/Atp1b1/Glrx3/Mllt6/Aco1/Fth1/Ndfip1
GO:0030835 GO:0030835 negative regulation of actin filament depolymerization 29 -0.7059779 -1.991154 0.0000505 0.0069549 0.0061601 1477 tags=45%, list=14%, signal=39% Add3/Twf1/Arpc2/Add1/Mphosph8/Specc1l/Carmil1/Mtpn/Capza2/Capg/Tpm1/Swap70/Rdx
GO:0007091 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 57 0.6292576 1.971442 0.0000631 0.0079956 0.0070819 1062 tags=28%, list=10%, signal=25% Ube2c/Ccnb1/Cit/Cdc6/Mad2l1bp/Plk1/Cenpe/Anapc7/Mad1l1/Anapc11/Trip13/Mad2l1/Pcid2/Cdt1/Ndc80/Nsmce2
GO:0006066 GO:0006066 alcohol metabolic process 183 -0.4304918 -1.667521 0.0000676 0.0080799 0.0071566 1918 tags=30%, list=18%, signal=25% Plpp2/Pecr/Acer3/Acadl/Gk/G6pdx/Aco2/Inpp5a/Abhd4/Clcn2/Lmf1/Ppip5k2/Apoe/Isyna1/Sc5d/Cyb5r3/Plpp3/Plcb3/Dab2/Itpk1/Inpp5e/Pcbd1/Slc5a3/Mogat2/Galk1/Fdx1/Plcd1/Spr/Sptlc2/Synj1/Hdlbp/Akr1b8/Srebf1/Acpp/Sptlc1/Plpp1/Slc37a2/Asah1/Inppl1/Apoc1/Pten/Tsku/Ldlrap1/Fech/Got1/Insig1/Fdxr/Aplp2/Prkaa2/Idh3g/Qdpr/Smpd1/Scp2/Idh3a/Idh1
GO:0060284 GO:0060284 regulation of cell development 300 -0.3810310 -1.549568 0.0000753 0.0084605 0.0074937 1900 tags=27%, list=18%, signal=23% Kdm1a/Dnm1l/Ankrd27/Lrp8/Bcar1/Nrg1/Trak1/Qk/Actn4/Tert/Plxnb2/Reck/Dleu2/Hif1a/Fxn/Ptpra/Apoe/Cux1/Ufl1/Spg20/Caprin1/Pafah1b1/Epha4/Psen1/Dab2/Tiam1/Pias2/Numbl/Arpc2/Runx1/Map6/Hdac2/Net1/Add1/Sema5b/Rapgef2/Mfn2/Dnajb11/Prtg/Etv5/Arhgef2/Axin2/Trim11/Fn1/Notch2/Tacstd2/Xlr3b/S100a10/Fbln1/Ppp3ca/Ctnna1/Synj1/Lyn/Cdc42/Actr2/Trib1/Obsl1/Trak2/Hdac4/Carmil1/Pten/Sema4b/Lrp2/Hmga2/Vcl/Id2/Khdc3/Calr/Skil/Eif2b2/Braf/Srrt/Dag1/Rnd2/Rtn4/Rab11a/F11r/Actr3/Myo5b/Tjp2/Marcks/Atxn1
GO:0090231 GO:0090231 regulation of spindle checkpoint 16 0.8242395 1.982389 0.0000812 0.0084605 0.0074937 1068 tags=56%, list=10%, signal=51% Ccnb1/Mad2l1bp/Mad1l1/Hsf1/Mad2l1/Pcid2/Cdt1/Ndc80/Aurka
GO:0008015 GO:0008015 blood circulation 188 -0.4301058 -1.669408 0.0000887 0.0085082 0.0075359 2261 tags=35%, list=21%, signal=28% Gclm/Sirt1/Jup/Ext2/Ier3/Gas6/Bin1/Slc9a1/Manf/Gsn/Dnm1l/Calm3/Eng/G6pdx/Ren1/Lnpep/Hif1a/Dsp/Slc4a5/Apoe/Atp1a1/Add3/Ocln/Adrb3/C2cd4a/Plcb3/Rbfox2/Atp6ap2/Chga/Atp2b1/Dsg2/Gna11/Smad3/Tbx20/Epas1/Dmd/Nisch/Emp2/Srebf1/Pebp1/P2rx4/Gpx1/Cdc42/Map2k3/Gna13/Hdac4/Ccn2/Calm2/Nav2/Amot/Pik3r1/Plec/Myl4/Id2/Mdm4/Tpm1/Hmox1/Gja1/Cxadr/Atp1b1/Glrx3/Ncf2/F11r/Akap12/Tjp2/Enpep
GO:2001169 GO:2001169 regulation of ATP biosynthetic process 16 -0.7869583 -1.927172 0.0001122 0.0095633 0.0084705 1204 tags=50%, list=11%, signal=44% Stat3/Parp1/Bcl2l1/Ndufc2/Eno1b/Eno1/Ak4/Vcp
GO:0010035 GO:0010035 response to inorganic substance 243 -0.3986072 -1.598642 0.0001165 0.0095988 0.0085020 1450 tags=22%, list=14%, signal=20% Lct/Abcb6/Fbxo7/Ncstn/Iqgap1/Atp7b/Blm/Parp1/Ahcyl1/Hdac2/Asph/Net1/Add1/Ucp2/Clic4/Cpne3/Txnrd2/Psap/Cpne8/Plcd1/Itgav/Fn1/Anxa11/Ass1/Prdx2/Ppp3ca/Fntb/P2rx4/Gpx1/Gapdh/Rtf2/Calm2/Krt8/Ppp1ca/Anxa7/Sigmar1/Gss/Alad/Plec/Id2/Prkaa2/Slc25a13/Ppif/Hmox1/Cdh1/Braf/Nfe2l2/Smpd1/Pdcd6/Glrx/Vcp/Glud1/Aco1/Kdm6b
GO:0048259 GO:0048259 regulation of receptor-mediated endocytosis 66 -0.5521934 -1.846000 0.0001519 0.0106242 0.0094102 2890 tags=52%, list=27%, signal=38% Apoc2/Lrpap1/Cd63/Mtmr2/Sdcbp/Pip5k1c/Ap2a1/Hip1r/Atad1/Pard3/Ankrd13a/Ap2m1/Hnrnpk/Nrg1/Anxa2/Scyl2/Flot1/Insr/Atxn2/Dab2/Ppp3r1/Itgav/Mkln1/Synj1/Ppt1/Apoc1/Cd2ap/Ldlrap1/Usp46/Pick1/Efnb2/Nsf/Nedd4/Arf1
GO:0042063 GO:0042063 gliogenesis 158 -0.4356657 -1.672251 0.0001670 0.0112356 0.0099517 2209 tags=32%, list=21%, signal=26% Spint1/Med12/Bin1/Dab2ip/Creb1/Dusp10/Arhgef7/Lrp8/Nsun5/Nrg1/Qk/Tert/Ptpra/Cdk6/Ufl1/Slc25a46/Pafah1b1/Epha4/Psen1/Erbb2/Plpp3/Ncstn/Stat3/Hdac2/Mfn2/Etv5/Ppp3r1/Dmd/Fn1/Otx2/Synj1/Lyn/P2rx4/Pals1/Pten/Srgap2/Lrp2/Phgdh/Pick1/Hmga2/Plec/Id2/Erbb3/Lamb1/Ptpn11/Eif2b2/Dag1/Rtn4/Actr3/Wdr1/Atxn1
GO:0006897 GO:0006897 endocytosis 289 -0.3780418 -1.538794 0.0001685 0.0112356 0.0099517 2382 tags=35%, list=22%, signal=28% Ap2a1/Appl2/Hip1r/Atad1/Vps28/Wasf2/Pard3/Rab17/Usp20/Clcn3/Ankrd13a/Cttn/Bin1/Amn/Atp9a/Lgals3/Rabep2/Gsn/Myh9/Atp5b/Ap2m1/Hnrnpk/Siglecf/Dnm1l/Calm3/Lrp8/Nrg1/Actn4/Anxa2/Gm12169/Scyl2/Arfgap1/Ehd4/Flot1/Apoe/Rab4a/Insr/Scarb2/Ctsl/Rab5c/Atxn2/Snx18/Ap4e1/Tpcn2/Dab2/Pikfyve/Bin3/Add1/Bin2/Pacsin2/Ehd1/Heatr5a/Pycard/Bcl2l1/Ppp3r1/Eps15/Itgav/Mkln1/Pacsin3/Prom2/Ehbp1/Becn1/Atp6v1h/Ap2s1/Ppp3ca/Fnbp1l/Synj1/Rab1a/Pstpip1/Clcn5/Cdc42/Ap3m1/Mfge8/Carmil1/Inppl1/Ppt1/Cap1/Apoc1/Cd2ap/Ldlrap1/Usp46/Lrp2/Sh3bp4/Pick1/Efnb2/Ezr/Rhov/Nsf/Canx/Ap2a2/Dppa1/Ncl/Actg1/Cd151/Dennd1a/Smpd1/Snx2/Nedd4/Clta/Arf1/Cltc
GO:0070848 GO:0070848 response to growth factor 319 -0.3596877 -1.473438 0.0001847 0.0116957 0.0103593 2309 tags=31%, list=22%, signal=25% Vsir/Bmpr1a/Usp9x/Tcf4/Sirt1/Ext2/Cd59a/Gas6/Zfhx3/Flrt1/Fgfr2/Bcl9l/Prkd2/Dab2ip/Jcad/Creb1/Tab1/Tgfbr1/Fer/Eng/Bcar1/Lats2/Itgb5/Hif1a/Ehd4/Gipc1/Strap/Grb10/Mars1/Stub1/Insr/Spg20/Ier2/Erbb2/Pml/Dab2/Iqgap1/Trim71/Klb/Mapk14/Stat3/Arpc2/Usp15/Parp1/Runx1/Nanog/Dusp3/Rapgef2/Col4a2/Cdc5l/Ppp2r5d/Cpne3/Sfrp1/Ehd1/Acvr2b/Smad3/Map3k1/Tbx20/Hivep1/Med1/Zfp36l2/Pdgfra/Foxh1/Dmd/Epb41l5/Sparc/Hhex/Notch2/Ptpn12/Ccn1/Slc9a6/Pals1/Map2k3/Frs2/Coro1b/Ccn2/Gdf3/Rab14/Rbpj/Tsku/Lrp2/Zyx/Nlk/Slc33a1/Got1/Msx2/Hspa5/Eef1a1/Gata3/Skil/Ptpn11/Acvr1b/Ncl/Xbp1/Pdcd5/Pdcd6/Nedd4/Pdcd4/Actr3
GO:0097581 GO:0097581 lamellipodium organization 58 -0.5731214 -1.879850 0.0003238 0.0166762 0.0147706 1215 tags=31%, list=11%, signal=28% Twf1/Arpc2/Bin3/Akirin1/Fscn1/Cdc42/Actr2/Coro1b/Hdac4/Nck2/Carmil1/Whamm/Srgap2/Pik3r1/Arpc5/Vcl/Snx2/Actr3
GO:0007369 GO:0007369 gastrulation 104 -0.4726302 -1.707256 0.0003792 0.0184792 0.0163675 1118 tags=23%, list=10%, signal=21% Nanog/Sfrp1/Acvr2b/Smad3/Cdc73/Txnrd1/Tgif1/Itgav/Epb41l5/Fn1/Otx2/Hhex/Macroh2a1/Frs2/Pou5f1/Dld/Amot/Gdf3/Hmga2/Ric8a/Dusp4/Dag1/Supt20/Kdm6b
GO:0042180 GO:0042180 cellular ketone metabolic process 122 -0.4534527 -1.664481 0.0003792 0.0184792 0.0163675 2237 tags=33%, list=21%, signal=26% Sirt1/Akr1b3/Akr1c14/Acadvl/Dgat2/Acadl/Gk/Erfe/Hnf4a/Kyat1/Clcn2/Glo1/Nmt1/Brca1/Ncor2/Dab2/Coq7/Coq10b/Mid1ip1/Stard3/Cpt1a/Comt/Akr1b8/Fabp3/Srebf1/Coq5/Slc37a2/Kdsr/Hsd17b10/Apoc1/Cbr3/Insig1/Fdxr/Elovl5/Kyat3/Fabp5/Aldoa/Ndufa9/Fh1/Scp2
GO:0005975 GO:0005975 carbohydrate metabolic process 325 -0.3563783 -1.461581 0.0003833 0.0184792 0.0163675 1884 tags=25%, list=18%, signal=21% Galt/Gk/Dlat/Khk/Erfe/G6pdx/Inpp5a/Gla/Hnf4a/B4galt1/Hif1a/Pgm2/Ppip5k2/Ogdh/Isyna1/Grb10/Mdh1/Glo1/Insr/Scarb2/Psen1/Taldo1/Slc39a14/Lctl/Itpk1/Inpp5e/Gys1/Dcxr/Klb/Mapk14/Stat3/Slc5a3/Pkm/Ugp2/Mogat2/Galk1/Slc23a2/Plcd1/Cpt1a/Pdha1/Nisch/Synj1/Pfkfb2/Idnk/Jmjd8/Fuca1/St3gal6/Ncoa2/Ddb1/Gapdh/Adipor1/Hdac4/Neu1/Inppl1/Edem1/Pten/Ppp1ca/Ppp1cb/Pik3r1/St6galnac4/Fbp2/Brat1/Got1/Prkaa2/Ppp4r3b/Eno1b/Pgd/B3galnt1/Fabp5/Braf/Aldoa/Fuca2/Eno1/Ppp1r2/Nudt5/Cltc/Maea/Supt20/Idh1/Hk2/Cs
GO:0018105 GO:0018105 peptidyl-serine phosphorylation 184 0.4282398 1.587149 0.0004389 0.0203630 0.0180361 1537 tags=23%, list=14%, signal=20% Epm2a/Ccnb1/Cdk1/Top1/Hax1/Ppp1r15a/Prkcd/Plk1/Csnk1e/Caprin2/Tfrc/Csnk1g1/Cab39/Ddit4/Ogt/Sgk3/Cdk2/Mast3/Mapk13/Mast1/Hdac6/Vrk1/Pbk/Stk38/Uhmk1/Map4k1/Wnk1/Aurka/Stk4/Prkdc/Gpd1l/Srpk2/Chek2/Sgk1/Mastl/Eif4g1/Tlk1/Mtor/Mknk2/Clk1/Sh2d3c/Csnk2a1
GO:0044282 GO:0044282 small molecule catabolic process 198 -0.3980496 -1.559001 0.0004867 0.0219308 0.0194247 1601 tags=23%, list=15%, signal=20% Apoe/Acox1/Etfb/Glo1/Abhd2/Pnp/Hibadh/Cpt2/Eci2/Crat/Urah/Inpp5e/Acat1/Galk1/Oat/Cpt1a/Echdc2/Synj1/Got2/Hadha/Pfkfb2/Idnk/Akr1b8/Crot/Hmgcl/Hadhb/Hsd17b10/Nudt19/Pex5/Pten/Cbr3/Got1/Etfa/Abcd4/Hadh/Eno1b/Gcat/Pgd/Qdpr/Eno1/Nudt5/Glud1/Scp2/Acaa2/Esd
GO:0042445 GO:0042445 hormone metabolic process 57 -0.5530648 -1.801144 0.0005011 0.0221524 0.0196210 1704 tags=35%, list=16%, signal=30% Ren1/Clcn2/Hif1a/Atp1a1/Stub1/Cyp2s1/Ctsl/Slc16a10/Dab2/Atp6ap2/Stard3/Fdx1/Med1/Pdgfra/Comt/Hsd17b10/Sgpl1/Gata3/Ptpn11/Scp2
GO:0035437 GO:0035437 maintenance of protein localization in endoplasmic reticulum 10 -0.8501288 -1.837722 0.0005562 0.0236928 0.0209854 266 tags=40%, list=2%, signal=39% Kdelr1/Insig1/Hspa5/Gja1
GO:0042254 GO:0042254 ribosome biogenesis 285 0.3927829 1.520017 0.0005899 0.0246815 0.0218611 2235 tags=34%, list=21%, signal=27% Rpl7l1/Exosc5/Nop16/Rsl24d1/Pop5/Nop10/Emg1/Rpp38/Rplp0/Eif6/Tsr2/Isg20l2/Rcl1/Snu13/Chd7/Dimt1/Mrto4/Wdr43/Wdr75/Nob1/Exosc1/Nup88/Rps7/Utp20/C1qbp/Utp4/Mak16/C1d/Rrn3/Mrpl22/Exosc7/Rpl6/Mrps7/Mdn1/Tent4b/Rps24/Rps27l/Mybbp1a/Aatf/Rpl11/Nol9/Ddx31/Gtf2h5/Krr1/Znhit3/Prkdc/Ipo4/Nip7/Rpl27/Ddx47/Rpl7a/Rexo4/Ddx51/Ppan/D1Pas1/Nat10/Mphosph6/Nhp2/Rpp25/Nol6/Utp15/Rps14/Ythdf2/Rps27/Rps17/Nop9/Rps25/Mrpl20/Tbl3/Rpl35/Pa2g4/Brix1/Cul4a/Mettl17/Tfb2m/LTO1/Utp18/Mtrex/Rpl24/Rrp1b/Bud23/Dhx37/Kri1/Rps15/Trmt112/Rps21/Shq1/Nol11/Rrp15/Surf6/Nle1/Riox1/Ercc2/Mettl16/Exosc8/Mterf3
GO:0032989 GO:0032989 cellular component morphogenesis 394 -0.3436198 -1.433541 0.0006199 0.0256253 0.0226970 2139 tags=27%, list=20%, signal=22% Mff/Flrt1/Opa1/Fgfr2/Kalrn/Dab2ip/Bsg/Creb1/Afg3l2/Mapt/Actn2/Hnrnpk/Kdm1a/Septin7/Dnm1l/Ankrd27/Ssbp1/Lrp8/Nrg1/Trak1/Plxnb2/Fxn/Flot1/Ephb6/Lama5/Apoe/Cux1/Spg20/Caprin1/Epha1/Slc25a46/Pafah1b1/Epha4/Psen1/Atxn2/Erbb2/Taok2/Tiam1/Pias2/Iqgap1/Coq7/Pikfyve/Numbl/Rbfox2/Map6/Raph1/Hdac2/Plaa/Sema5b/Rapgef2/Vasp/Pdlim5/Slc23a2/Mfn2/Pacsin2/Prtg/Bcl2l1/Pdgfra/Enah/Dmd/Fn1/Otx2/Xlr3b/Slc9a6/Ppp3ca/Tbpl1/Llph/Cdc42/Pals1/Actr2/Tet1/Mul1/Obsl1/Trak2/Coro1b/Krt8/Pten/Sema4b/Tsku/Srgap2/Lrp2/Smn1/Efnb2/Plec/Vcl/Tpm1/Gata3/Skil/Ptpn11/Apbb1/Eif2b2/Braf/Gja1/Actg1/Dag1/Rnd2/Rtn4/Csrp1/Snx2/Nedd4/Rab11a/Actr3/Myo5b/Wdr1/Marcks/Igf2bp1
GO:0007167 GO:0007167 enzyme linked receptor protein signaling pathway 452 -0.3301339 -1.395435 0.0006836 0.0269171 0.0238412 2370 tags=31%, list=22%, signal=25% Appl2/Cdh3/C1qtnf12/Hip1r/Vsir/Bmpr1a/Usp9x/Tcf4/Sirt1/Wwtr1/Eif4ebp2/Cd59a/Gas6/Flrt1/Opa1/Fgfr2/Bcl9l/Tyro3/Prkd2/Dab2ip/Jak1/Sub1/Jcad/Creb1/Tab1/C2cd5/Tgfbr1/Cnot9/Rab7/Fer/Erfe/Eng/Bcar1/Nrg1/Stat6/Meg3/Lats2/Hnf4a/Itgb5/Lnpep/Hif1a/Ephb6/Gipc1/Ptpra/Strap/Col4a1/Errfi1/Gprc5a/Grb10/Stub1/Insr/Chmp6/Spg20/Epha1/Eif4ebp1/Epha4/Psen1/Slc39a14/Erbb2/Pml/Dab2/Tiam1/Slc9a3r1/Iqgap1/Trim71/Klb/Mapk14/Stat3/Usp15/Parp1/Nanog/Ppm1l/Dusp3/Rapgef2/Col4a2/Ppp2r5d/Cpne3/Sfrp1/Mfn2/Acvr2b/Smad3/Map3k1/Tbx20/Hivep1/Pdgfra/Foxh1/Tgif1/Fam72a/Hhex/Notch2/Ptpn12/Ccn1/Slc9a6/Lyn/Srebf1/Socs1/Pals1/Igsf1/Frs2/Adipor1/Nck2/Ccn2/Pdgfa/Socs2/Gdf3/Inppl1/Phf14/Rab14/Pten/Rbpj/Nup93/Tsku/Sgpl1/Lrp2/Zyx/Pik3r1/Efnb2/Nlk/Slc33a1/Got1/Msx2/Erbb3/Mvp/Hspa5/Gata3/Skil/Ptpn11/Acvr1b/Braf/Nucks1/Rtn4/Xbp1/Pdcd6/Nedd4/Glrx/Pdcd4/Marcks/Atxn1
GO:0034762 GO:0034762 regulation of transmembrane transport 218 -0.3813117 -1.508139 0.0006978 0.0270255 0.0239373 1835 tags=23%, list=17%, signal=20% Erfe/Calm3/G6pdx/Clcnkb/Tert/Clcn2/Grb10/Insr/Clic1/Ocln/Ubqln1/Psen1/Tmem37/Crbn/Tpcn2/Slc31a2/Slc9a3r1/Clic3/Mapk14/Cox17/Ahcyl1/Asph/Clic4/Mfn2/Dmd/Ywhae/Sestd1/Oga/Lyn/Calm2/Ahnak/Sco1/Pten/Kcng4/Pea15a/Erbb3/Ppif/Ptpn11/Fabp5/Braf/Gja1/Atp1b1/Arl6ip5/Nfe2l2/Nedd4/Glrx/Taco1/Slc25a4/Arf1/Wdr1/Hk2
GO:0007492 GO:0007492 endoderm development 42 -0.5921110 -1.806847 0.0007264 0.0276735 0.0245112 1466 tags=40%, list=14%, signal=35% Leo1/Dab2/Nanog/Smad3/Cdc73/Itgav/Epb41l5/Fn1/Otx2/Hhex/Macroh2a1/Ssbp3/Pou5f1/Gdf3/Hmga2/Dusp4/Ankrd17
GO:0051983 GO:0051983 regulation of chromosome segregation 78 0.5208787 1.722121 0.0007390 0.0279266 0.0247354 776 tags=21%, list=7%, signal=19% Ube2c/Kif2c/Ccnb1/Cit/Cdc6/Mad2l1bp/Plk1/Cenpe/Pum2/Anapc7/Mad1l1/Anapc11/Trip13/Mad2l1/Pcid2/Cdt1
GO:0022600 GO:0022600 digestive system process 35 -0.6170038 -1.806703 0.0008667 0.0310021 0.0274594 1608 tags=31%, list=15%, signal=27% Strap/Ugcg/Slc22a21/Sct/Mogat2/Copa/Ezr/F11r/Tjp2/Epb41/Aco1
GO:0006888 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 100 -0.4617934 -1.658351 0.0009815 0.0323177 0.0286247 2194 tags=39%, list=21%, signal=31% Tmed7/Bet1/Ergic2/Trappc5/Stx18/Copb1/Rint1/Mia2/Lmf1/Mppe1/Yif1a/Ergic3/Tfg/Tmed10/Yipf5/Copg2/Hyou1/Klhl12/Sec23a/Nrbp1/Lman2/Sec13/Ier3ip1/Rab1a/Copa/Arcn1/Sec23b/Pgap1/Copb2/Copg1/Lman1/Sec24d/Mia3/Whamm/Kdelr1/Insig1/Pdcd6/Vcp/Arf1
GO:0070979 GO:0070979 protein K11-linked ubiquitination 25 0.7020926 1.867267 0.0010592 0.0337633 0.0299052 456 tags=24%, list=4%, signal=23% Ube2c/Ube2b/Ube2w/Anapc7/Ube2t/Anapc11
GO:0008285 GO:0008285 negative regulation of cell population proliferation 345 -0.3445267 -1.417998 0.0010870 0.0341847 0.0302784 1751 tags=23%, list=16%, signal=20% Smarca2/Pkn1/Aimp1/Hnf4a/Tert/B4galt1/Fbxo2/Optn/Apoe/Sdc4/Cdk6/Arid2/Ggnbp2/Ctsl/Erbb2/Pml/Fzd5/Dab2/Cherp/Slc9a3r1/Kank2/Stat3/Runx1/Hdac2/Gsdme/Asph/Kdf1/Akirin1/Rapgef2/Gtpbp4/Sfrp1/Mfn2/Smad3/Cdc73/Irf6/Tfdp1/Med1/Tmem127/Tgif1/Glmn/Axin2/Sparc/Comt/Becn1/Fbln1/Spint2/Ctnna1/Lyn/Lmna/Tes/Fntb/Gna13/Trib1/Ifi30/Strn/Hdac4/Inppl1/Phf14/Pten/Rbpj/Sh3bp4/Pik3r1/Cops8/Tbrg1/Efnb2/Msx2/Tpm1/Btg1/Atp5a1/Gata3/Hmox1/Cdh1/Gja1/Cxadr/Pdcd5/Ptges/Intu/Pdcd4/Fth1/Ndfip1/Pttg1
GO:0045995 GO:0045995 regulation of embryonic development 38 -0.5940457 -1.791322 0.0012430 0.0374704 0.0331886 1713 tags=37%, list=16%, signal=31% Hnf4a/Lama5/Insr/Pafah1b1/Utp25/Tgif1/Otx2/Amot/Rab14/Trip12/Khdc3/Hspa5/Dag1/Nfe2l2
GO:0046034 GO:0046034 ATP metabolic process 189 -0.3891630 -1.511404 0.0012714 0.0374704 0.0331886 2204 tags=35%, list=21%, signal=28% Atp5o/Ier3/Ndufb8/Nmnat1/Cox5a/Arl2/Atp5b/Uqcrb/Gpi1/Galt/Sdhc/Dnm1l/Dmac2l/Ndufb9/Khk/Cycs/Hif1a/Fxn/Ogdh/Pde12/Sdha/1700066M21Rik/Insr/Psen1/Atp6v1a/Ndufs1/Coq7/Stat3/Parp1/Atp5j2/Pkm/Atp6v1b2/Galk1/Ndufv1/Bcl2l1/Chchd10/Cox7a2l/Cox5b/Pfkfb2/Jmjd8/Cyct/Cox6a1/Ndufs7/Gapdh/Ndufc2/Hdac4/Dld/Cyc1/Atp5g3/Cox4i1/Atp5d/Atp5pb/Prkaa2/Slc25a13/Atp5a1/Ppif/Eno1b/Ampd2/Uqcrc1/Aldoa/Atp1b1/Eno1/Ak4/Nudt5/Vcp/Hk2
GO:0001667 GO:0001667 ameboidal-type cell migration 222 -0.3698735 -1.463308 0.0014183 0.0397981 0.0352503 2077 tags=31%, list=19%, signal=25% Prkd2/Dab2ip/Bsg/Capn7/Lgals8/Jcad/Dusp10/Myh9/Atp5b/Tgfbr1/Gpi1/Fer/Bcar1/Pkn1/Hif1a/Gipc1/Lama5/Apoe/Sdc4/Tns1/Pafah1b1/Plpp3/Pml/Iqgap1/Kank2/Sema5b/Arhgdib/Amotl2/Itgav/Epb41l5/Sparc/Fn1/Pfn2/Pecam1/Tacstd2/Svbp/Ago2/Emp2/P2rx4/Gpx1/Cdc42/Map2k3/Adipor1/Coro1b/Amot/Mia3/Cap1/Pten/Sema4b/Sgpl1/Srgap2/Efnb2/Plec/Pdlim1/Atp5a1/Calr/Gata3/Hmox1/Ptpn11/Acvr1b/Braf/Ric8a/Rtn4/Nfe2l2/Pdcd6/Rab11a/Actr3/Akap12
GO:0019693 GO:0019693 ribose phosphate metabolic process 239 -0.3661830 -1.460392 0.0015280 0.0413887 0.0366592 2035 tags=29%, list=19%, signal=24% Dgat2/Arl2/Acss2/Atp5b/Gpi1/Galt/Dmac2l/Dlat/Khk/G6pdx/Acot11/Hnf4a/Adsl/Hif1a/Ogdh/Nudt14/Suclg1/Rfk/Insr/Gnai3/Pnp/Prps2/Psen1/Urah/Coasy/Stat3/Umps/Parp1/Atp5j2/Pkm/Acat1/Acot9/Galk1/Atp2b2/Bcl2l1/Pdha1/Dcakd/Pfkfb2/Jmjd8/Pfas/Gapdh/Ndufc2/Crot/Hmgcl/Hdac4/Dld/Nudt18/Atp5g3/Nudt19/Atp5d/Sucla2/Atp5pb/Prkaa2/Slc25a13/Atp5a1/Eno1b/Ampd2/Aldoa/Eno1/Ak4/Nudt5/Vcp/Gmps/Scp2/Gmpr/Adss/Hk2/Cs/Acaa2
GO:0072659 GO:0072659 protein localization to plasma membrane 199 -0.3746258 -1.463457 0.0016186 0.0428506 0.0379540 2168 tags=30%, list=20%, signal=24% Gas6/Vamp3/Amn/Acsl3/Kalrn/Bsg/Lgals3/C2cd5/Actn2/Ap2m1/Ttc7b/Sys1/Kif13a/Rab7/Anxa2/Ehd4/Flot1/Lama5/Optn/Blzf1/Zdhhc3/Vti1b/Stx8/Dab2/Slc9a3r1/Lypla1/Myl12a/Rapgef2/Ehd1/Sec23a/Vps35/Bcl2l1/Hectd1/S100a10/Krt18/Emp2/Pals1/Plekhf1/Stx7/Gga2/Sco1/Ldlrap1/Pik3r1/Pgrmc1/Ezr/Nsf/Efr3a/Stx3/Cdh1/Atp1b1/Arl6ip5/Rab11a/Cltc/F11r/Actr3/Scp2/Rdx/Myo5b/Sqstm1
GO:0006734 GO:0006734 NADH metabolic process 26 -0.6505311 -1.776466 0.0016587 0.0429426 0.0380355 940 tags=31%, list=9%, signal=28% Nudt12/Slc37a2/Dlst/Idh3g/Eno1b/Eno1/Vcp/Idh3a
GO:0010975 GO:0010975 regulation of neuron projection development 283 -0.3493779 -1.425541 0.0018037 0.0455615 0.0403551 1869 tags=25%, list=18%, signal=21% Dnm1l/Ankrd27/Lrp8/Nrg1/Trak1/Qk/Plxnb2/Dleu2/Fxn/Prkcsh/Apoe/Cux1/Mob2/Spg20/Scarb2/Caprin1/Pafah1b1/Epha4/Psen1/Fbxo7/Dab2/Tiam1/Pias2/Iqgap1/Numbl/Dync1i2/Twf1/H2-K1/Map6/Hdac2/Sema5b/Rapgef2/Pdlim5/Ppp2r5d/Sfrp1/Mfn2/Ehd1/Dmd/Mboat1/Fn1/Xlr3b/Ppp3ca/Lyn/Actr2/Obsl1/Trak2/Neu1/Inppl1/Itga6/Pten/Sema4b/Tsku/Smn1/H2-D1/Efnb2/Khdc3/Hspa5/Eef1a1/Gata3/Skil/Apbb1/Eif2b2/Braf/Rnd2/Rtn4/Nfe2l2/Nedd4/Rab11a/Actr3/Myo5b/Marcks
GO:0071260 GO:0071260 cellular response to mechanical stimulus 17 -0.7312854 -1.821056 0.0018085 0.0455615 0.0403551 790 tags=41%, list=7%, signal=38% Piezo1/Cnn2/Plec/Got1/Ptpn11/Dag1/F11r
GO:0097006 GO:0097006 regulation of plasma lipoprotein particle levels 36 -0.5835931 -1.737065 0.0018834 0.0462081 0.0409278 2890 tags=56%, list=27%, signal=41% Apoc2/Abca1/Lrpap1/Mfsd2a/Commd1/Dgat1/Soat1/Lpcat3/Acsl3/Dgat2/Hnrnpk/Anxa2/Lmf1/Apoe/Cnpy2/Ehd1/Apoc1/Ldlrap1/Fech/Arf1
GO:0098662 GO:0098662 inorganic cation transmembrane transport 276 -0.3515691 -1.430453 0.0019876 0.0482574 0.0427430 2239 tags=28%, list=21%, signal=23% Ndufa4/Clcn3/Atp5o/Itpr3/Gas6/Bin1/Opa1/Slc9a1/Phb2/Afg3l2/Atp5b/Actn2/Maip1/Calm3/G6pdx/Steap3/Atp12a/Atp6v0a2/Slc35g1/Abcb7/Atp1a1/Slc39a11/Abcb6/Slc6a14/Ubqln1/Slc39a14/Tmem37/Crbn/Trpm6/Atp6v1a/Tpcn2/Letm1/Slc31a2/Cherp/Slc9a3r1/Slc6a13/Atp7b/Cox17/Slc39a7/Atp5j2/Asph/Atp6v1b2/Slc6a8/Atp2b1/Mcur1/Atp2b2/Dmd/Itgav/Ywhae/Panx1/Sestd1/Atp6v1h/Slc9a6/Abcb8/Slc39a10/Lyn/P2rx4/Ndufs7/Tcn2/Calm2/Atp5g3/Atp6v0c/Ahnak/Sco1/Pten/Atp5d/Kcng4/Tmco1/Atp5pb/Atp5a1/Ppif/Slc24a5/Atp1b1/Nedd4/Glrx/Taco1/Slc25a4/Arf1
GO:0090068 GO:0090068 positive regulation of cell cycle process 165 0.4171580 1.528114 0.0020049 0.0484275 0.0428936 1422 tags=24%, list=13%, signal=21% Ube2c/Ccnb1/Cit/Cdc6/Cdk1/Poc1a/Cd28/Mad2l1bp/Ube2b/Cenpe/Anapc7/Dazl/Slf2/Hspa2/Mad1l1/Anapc11/Kif23/Mad2l1/Dbf4/Pcid2/Sox15/Nusap1/Cdt1/Brd4/Rpl17/Sphk1/Ddx39b/Ndc80/Ect2/Nsmce2/Aurka/Adam17/Lsm10/Chek2/Rgcc/Eif4g3/Wnt10b/D1Pas1/Eif4g1
active vs ctrl - Molecular Function GO
ID Description setSize enrichmentScore NES pvalue p.adjust qvalues rank leading_edge core_enrichment
GO:0016491 GO:0016491 oxidoreductase activity 414 -0.4400765 -1.838881 0.0000000 0.0000001 0.0000001 1690 tags=27%, list=16%, signal=24% 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
GO:0003779 GO:0003779 actin binding 231 -0.4377037 -1.718392 0.0000012 0.0005063 0.0004410 1255 tags=22%, list=12%, signal=20% Iqgap1/Twf1/Arpc2/Add1/Vasp/Pdlim5/Flnb/Enah/Dmd/Myo10/Pfn2/Panx1/Ctnna1/Klhl3/Pstpip1/Fscn1/Tmsb10/Actr2/Epb41l1/Coro1b/Tpm4/Cnn2/Inppl1/Cap1/Whamm/Capza2/Ipp/Pick1/Ppp1r18/Ezr/Capg/Msrb2/Plec/Arpc5/Myl4/Vcl/Pdlim7/Gmfb/Pdlim1/Tpm1/Dag1/Actr3/Rdx/Myo5b/Maea/Epb41/Arpc1b/Wdr1/Marcks/Eef2
GO:0051287 GO:0051287 NAD binding 42 -0.6768022 -2.039598 0.0000036 0.0009866 0.0008593 1636 tags=48%, list=15%, signal=40% Me1/Mdh1/Cyb5r3/Hibadh/Parp1/Ndufv1/Htatip2/Hadha/Aldh2/Gapdh/Dld/Hsd17b10/Grhpr/Phgdh/Hadh/Idh3g/Qdpr/Glud1/Idh3a/Idh1
GO:0022853 GO:0022853 active ion transmembrane transporter activity 114 -0.4908940 -1.781564 0.0000597 0.0093093 0.0081081 2336 tags=41%, list=22%, signal=33% Atp6v1g1/Slc6a15/Anxa5/Clcn3/Slc37a4/Slc9a1/Cox5a/Uqcr11/Atp5b/Slc26a11/Slc26a2/Slc28a3/Slc5a4b/Atp12a/Slc4a5/Atp1a1/Slc39a14/Atp6v1a/Letm1/Slc6a13/Atp7b/Slc5a3/Slc6a8/Atp2b1/Slc23a2/Slc19a1/Atp2b2/Slc5a11/Cox7a2l/Surf1/Slc20a1/Atp6v1h/Slc9a6/Clcn5/Cox6a1/Cox7b/Slc37a2/Cyc1/Atp6v0c/Cox4i1/Slc25a5/Slc33a1/Slc24a5/Uqcrfs1/Atp1b1/Slco2a1/Slc25a4
GO:0005200 GO:0005200 structural constituent of cytoskeleton 39 -0.6589617 -1.957012 0.0001338 0.0116660 0.0101606 1199 tags=38%, list=11%, signal=34% Arpc2/Add1/Tubb4b/Tuba1c/Tuba3a/Tuba1a/Actr2/Plec/Arpc5/Tpm1/Tubb2a/Actg1/Actr3/Arpc1b/Tuba4a
GO:0035254 GO:0035254 glutamate receptor binding 30 -0.6923241 -1.966388 0.0001490 0.0116660 0.0101606 1838 tags=50%, list=17%, signal=41% Ptpn4/Calm3/Flot1/Rab4a/Slc9a3r1/Arpc2/Myl12a/Atp2b2/Pten/Pick1/Nsf/Canx/Nedd4/Myo5b/Sqstm1
GO:0008289 GO:0008289 lipid binding 392 -0.3469108 -1.438566 0.0002381 0.0161807 0.0140929 2204 tags=30%, list=21%, signal=25% Atp5o/Itpr3/Gas6/Psmb4/Bin1/Arhgdia/Opa1/Dab2ip/Manf/Gsta4/Lamc1/Stard10/Gsn/Phb2/Gstp1/C2cd5/Actn2/Ap2m1/Dnm1l/Mitd1/Cibar1/Fer/Sdcbp2/Acot11/Phf12/Anxa2/Hnf4a/Gm12169/Sap30l/Bdh1/Apoe/Acox1/Atp1a1/Phlda1/Hs1bp3/Insr/Scarb2/Arfip2/Cd55/Snx19/Snx18/Tpcn2/Grb7/Fzd5/Dab2/Tiam1/Iqgap1/Pex3/Twf1/Bin3/Gsdme/Osbpl1a/Rapgef2/Bin2/Cpne3/Pacsin2/Psap/Stard3/Arhgef5/Map3k1/Cpne8/Plcd1/Tirap/Snx15/Tecpr1/Pacsin3/Anxa11/Prom2/Nisch/Wdfy1/Pfn2/Sestd1/Fnbp1l/Chmp3/Got2/Lyn/Laptm4b/Fabp3/Pebp1/Gltp/Rnf34/Plekhf1/Zranb2/Mfge8/Arhgap9/Atp5g3/Inppl1/Stard3nl/Ppt1/Cyth3/Hsd17b10/Apoc1/Anxa7/Ldlrap1/Pick1/Psma1/Pgrmc1/Capg/Insig1/Lamb1/Ap2a2/Unc119b/Plekhb2/Dppa1/Stx3/Atg2a/Tpp1/Fabp5/Gpaa1/Dennd1a/Snx2/Anxa4/Vdac2/Vcp/Scp2/Epb41/Marcks
GO:0016408 GO:0016408 C-acyltransferase activity 14 -0.7969305 -1.900609 0.0003948 0.0208273 0.0181398 1109 tags=57%, list=10%, signal=51% Acat1/Sptlc2/Hadha/Sptlc1/Hadhb/Gcat/Scp2/Acaa2
GO:0030544 GO:0030544 Hsp70 protein binding 34 0.6546009 1.847957 0.0006876 0.0292412 0.0254681 1489 tags=35%, list=14%, signal=30% Ficd/Cdk1/Tfrc/Stip1/Dnajb1/Dnajb2/Fkbp1a/Mvd/Fgf1/Dnajb14/Dnajc18/Dnajb9
GO:0015078 GO:0015078 proton transmembrane transporter activity 69 -0.5237612 -1.735845 0.0007158 0.0292412 0.0254681 2407 tags=45%, list=23%, signal=35% Atp6v1g1/Atp5h/Clcn3/Atp5o/Slc9a1/Cox5a/Uqcr11/Atp5b/Atp12a/Atp6v0a2/Atp6v1a/Letm1/Atp5j2/Cox7a2l/Surf1/Atp6v1h/Slc9a6/Clcn5/Cox6a1/Cox7b/Cyc1/Atp5g3/Atp6v0c/Cox4i1/Atp5d/Slc25a5/Slc33a1/Atp5pb/Atp5a1/Uqcrfs1/Slc25a4
GO:0050839 GO:0050839 cell adhesion molecule binding 122 -0.4422038 -1.614392 0.0008925 0.0317725 0.0276728 2585 tags=46%, list=24%, signal=35% Afdn/Lama3/Cdh23/Cadm1/L1cam/P4hb/Nectin2/Cdh3/Jup/Jam2/Bsg/Lgals8/Myh9/Msn/Fer/Rpsa/Nrg1/Itgb5/B4galt1/Dsp/Lama5/Psen1/Plpp3/Dab2/Adam15/Tbc1d2/Dsg2/Prtg/Dmd/Itgav/Fn1/Nisch/Ccn1/Tspan8/Fbln1/Ctnna1/Lyn/Emp2/P2rx4/Mfge8/Ccn2/Itga6/Ppp1ca/Anxa7/Cd2ap/Ezr/Lamb1/Calr/Ptpn11/Cdh1/Cxadr/Cd151/Epcam/Rtn4/F11r/Tjp2
GO:0005504 GO:0005504 fatty acid binding 21 -0.6883425 -1.802047 0.0011169 0.0317725 0.0276728 2535 tags=67%, list=24%, signal=51% Dbt/Dgat1/Gstp2/Arhgdia/Gsta4/Gstp1/Hnf4a/Acox1/Insr/Fabp3/Apoc1/Stx3/Fabp5/Scp2
GO:0042169 GO:0042169 SH2 domain binding 25 -0.6723351 -1.819857 0.0012827 0.0327498 0.0285239 485 tags=24%, list=5%, signal=23% Pag1/Inppl1/Arhgap5/Nlk/Dag1/Sqstm1
active vs ctrl - Cellular Component GO
ID Description setSize enrichmentScore NES pvalue p.adjust qvalues rank leading_edge core_enrichment
GO:0043209 GO:0043209 myelin sheath 160 -0.5948575 -2.275007 0.0000000 0.0000000 0.0000000 1955 tags=46%, list=18%, signal=38% Atp5b/Gpi1/Msn/Septin7/Dlat/Calm3/Ywhag/Cycs/Prdx1/Aco2/Tcp1/Anxa2/Cct2/Actr1a/Atp1a1/Sdha/Mdh1/Erbb2/Atp6v1a/Ndufs1/Pkm/Atp6v1b2/Ehd1/Uba52/Tubb4b/Pdha1/Uqcrc2/Ass1/Prdx2/Cox5b/Got2/Tuba1a/Gnb1/Pebp1/Fscn1/Cdc42/Cox6a1/Pals1/Gapdh/Dld/Calm2/Pdia3/Dlst/Immt/Pten/Serinc5/Phgdh/Ezr/Ubc/Slc25a5/Plec/Sucla2/Atp5pb/Nsf/Canx/Atp5a1/Hspa5/Hspa9/Eef1a1/Cdh1/Uqcrc1/Actg1/Uqcrfs1/Aldoa/Atp1b1/Rtn4/Eno1/Vdac2/Slc25a4/Vcp/Cltc/Idh3a/Rdx/Wdr1
GO:0005911 GO:0005911 cell-cell junction 250 -0.5025383 -1.992132 0.0000000 0.0000000 0.0000000 1280 tags=28%, list=12%, signal=25% Fzd5/Tiam1/Iqgap1/Pikfyve/Atp7b/Twf1/Add1/Ccdc85b/Patj/Clic4/Rapgef2/Uba1/Vasp/Pdlim5/Pacsin2/Amotl2/Dsg2/Ssx2ip/Rap2c/Arhgef2/Epb41l5/Specc1l/Pecam1/Panx1/Ppp3ca/Ctnna1/Lyn/Rap2b/Fscn1/Cdc42/Pals1/Frs2/Strn/Amot/Ccdc85c/Sympk/Dnmbp/Krt8/Cyth3/Ahnak/Ppp1ca/Cd2ap/Zyx/Pik3r1/Lsr/Ddx6/Vcl/Cldn6/Tnks1bp1/Pdlim7/Pdlim1/Cgnl1/Stx3/Cdh1/Cgn/Perp/Gja1/Actg1/Cxadr/Ybx3/Cldn4/Gjb3/Atp1b1/Dag1/Epcam/Frmd4b/F11r/Actr3/Tjp2/Wdr1
GO:0045177 GO:0045177 apical part of cell 214 -0.4697306 -1.826638 0.0000002 0.0000255 0.0000196 2647 tags=47%, list=25%, signal=36% Abcg2/Pard6a/Epb41l4b/Afdn/Slc4a2/Dram2/Cdh23/Cetn2/Slc3a2/Exoc1/Ap2a1/Slc44a4/Myl12b/Hip1r/Pard3/Usp9x/Rab17/Dpp4/Clcn3/Itpr3/Vamp3/Amn/Slc9a1/Slc7a1/Tchp/Slc2a1/Tgfbr1/Msn/Slc26a2/Prkab2/Nrg1/Birc5/Ren1/Pard6b/Atp12a/Slc4a5/Atp1a1/Cep164/Slc22a21/Ocln/Ctsl/Cd55/Psen1/Slc39a14/Erbb2/Trpm6/Atp6v1a/Dab2/Slc9a3r1/Itpk1/Atp7b/Atp6ap2/Ahcyl1/Atp6v1b2/Patj/Clic4/Rapgef2/Atp2b1/Slc23a2/Slc19a1/Amotl2/Dsg2/Atp2b2/Fn1/Prom2/Abcc1/Ooep/Svbp/Emp2/Slc29a1/Pebp1/P2rx4/Clcn5/Cdc42/Acpp/Pals1/Plpp1/Slc16a1/Pdia3/Rab14/Pten/Lrp2/Stxbp2/Ezr/Plec/Erbb3/Khdc3/Prkaa2/Stx3/Cdh1/Gja1/Actg1/Cldn4/Atp1b1/Epcam/Anxa4/Rdx/Myo5b/Enpep/Plet1
GO:0005938 GO:0005938 cell cortex 184 -0.4770757 -1.845842 0.0000007 0.0000794 0.0000611 2453 tags=38%, list=23%, signal=30% Dlc1/Exoc1/Rtkn/Stxbp6/Tpm3/Dync1h1/Myl12b/Hip1r/Pard3/Llgl2/Rhod/Myh10/Cttn/Fgfr2/Tchp/Gsn/C2cd5/Myh9/Actn2/Slc2a1/Septin11/Hnrnpk/Septin7/Gnai1/Fryl/Crip2/Actn4/Anxa2/Pard6b/Flot1/Exoc2/Gipc1/Cnksr1/Actr1a/Add3/Usp2/Arfip2/Pafah1b1/Psen1/Iqgap1/Asph/Kdf1/Dmd/Mkln1/Ooep/Pstpip1/Actr2/Tpm4/Ccn2/Cap1/Mpp1/Cd2ap/Capza2/Khdc3/Eef1a1/Eno1b/Cdh1/Ncl/Rnd2/Eno1/Nedd4/Clta/Rnd3/Rdx/Myo5b/Maea/Epb41/Ndfip1/Wdr1/Marcks
GO:0015629 GO:0015629 actin cytoskeleton 279 -0.4260082 -1.713601 0.0000015 0.0001322 0.0001017 1255 tags=22%, list=12%, signal=20% Iqgap1/Twf1/Arpc2/Bin3/Myl12a/Dctn3/Add1/Lpp/Pdlim5/Bin2/Flnb/Map3k1/Enah/Dmd/Arhgef2/Myo10/Specc1l/Ehbp1/Ptpn12/Ctnna1/Pstpip1/Fscn1/Actr2/Coro1b/Hdac4/Tpm4/Cnn2/Carmil1/Amot/Gng12/Cap1/Ahnak/Mtpn/Cd2ap/Capza2/Zyx/Ezr/Capg/Arpc5/Myl4/Vcl/Tnks1bp1/Pdlim7/Pdlim1/Tpm1/Eef1a1/Swap70/Cgnl1/Ptpn11/Cdh1/Cgn/Actg1/Aldoa/Csrp1/Actr3/Rdx/Myo5b/Maea/Epb41/Arpc1b/Wdr1/Marcks
GO:0140534 GO:0140534 endoplasmic reticulum protein-containing complex 114 -0.5306618 -1.932391 0.0000048 0.0003582 0.0002756 1920 tags=35%, list=18%, signal=29% Ormdl2/Sel1l/Rint1/Nploc4/Prkcsh/Sec61a2/Rpn2/Pigs/Sec61a1/Tap2/Stt3b/Piga/H2-K1/Stt3a/Emc9/Emc2/Hyou1/Magt1/Dnajb11/Hsd17b12/Sptlc2/Pigyl/Ddost/Ppib/Sptlc1/Pdia6/Sdf2l1/Pdia3/Selenos/H2-D1/Rpn1/Pdia4/Insig1/Hspa5/Calr/Hsp90b1/Gpaa1/Vcp/Emc8/Spcs3
GO:0098590 GO:0098590 plasma membrane region 497 -0.3550143 -1.506856 0.0000068 0.0004576 0.0003520 1959 tags=36%, list=18%, signal=30% 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
GO:0043292 GO:0043292 contractile fiber 99 -0.5297431 -1.887550 0.0000187 0.0008648 0.0006654 1952 tags=36%, list=18%, signal=30% Actn2/Slc2a1/Calm3/Simc1/Actn4/Myh7b/Sdc4/Stub1/Psen1/Twf1/Dek/Myl12a/Pdlim5/Cst3/Dmd/Pecam1/Ppp3ca/Hdac4/Calm2/Lman1/Krt8/Ahnak/Sco1/Plec/Myl4/Vcl/Pdlim7/Pdlim1/Tpm1/Gja1/Actg1/Aldoa/Dag1/Csrp1/Glrx3/Arf1
GO:0098857 GO:0098857 membrane microdomain 186 -0.4423869 -1.705367 0.0000230 0.0009895 0.0007613 2002 tags=34%, list=19%, signal=28% Mapt/Cavin1/Atp5b/Slc2a1/Tgfbr1/Plpp2/Gnai1/Lrp8/Stat6/Anxa2/Flot1/Sdc4/Atp1a1/Insr/Gnai3/Cd55/Psen1/Erbb2/Plpp3/Pag1/Lamtor3/Slc9a3r1/Iqgap1/Pikfyve/Atp2b1/Pacsin2/Ctsd/Prtn3/Atp2b2/Plcd1/Dmd/Prom2/Pecam1/S100a10/Cr1l/Ctnna1/Lyn/Tuba1a/Emp2/Rap2b/Plpp1/Ppp2r1b/Lamp2/Ppt1/Ahnak/Lrp2/H2-D1/Ezr/Slc25a5/Vcl/Atp5a1/Eno1b/Hmox1/Ptpn11/Cdh1/Tpp1/Gja1/Cxadr/Atp1b1/Dag1/Nedd4/Vdac2/Slc25a4/Eef2
GO:0005615 GO:0005615 extracellular space 351 -0.3767872 -1.547444 0.0000276 0.0010829 0.0008331 2335 tags=35%, list=22%, signal=28% C1qtnf12/Xylt2/Raet1a/Anxa5/Plau/St14/Akr1b3/Cd59a/Pla2g15/Susd2/Serpinb9b/Gas6/Amn/Arhgdia/Flrt1/Gm8909/Lgals3/Pcsk1n/Manf/Gsn/Gpi1/Smpdl3b/Gcnt1/Erfe/Eng/Lrp8/Nrg1/Egfl7/Gla/Anxa2/Aimp1/Ren1/Arsa/Raet1e/Smpdl3a/Lama5/Apoe/Tpsg1/Col4a1/Gprc5a/Rab4a/Clic1/Il4ra/Ctsl/Abcb6/Snx18/Pros1/Sct/Smoc1/S100a11/Atp6ap2/Adam15/H2-K1/Liph/Chga/Nucb1/Itm2b/Plaa/Pnliprp2/Col4a2/Sfrp1/Cst3/Ctsd/Dnajb11/Psap/Prtn3/Sparc/Fn1/Lman2/Pecam1/Tacstd2/S100a10/Fbln1/Cpm/Hdlbp/Krt18/Copa/Ago2/Rap2b/Fabp3/Pebp1/Acpp/Mtcl1/Pdia6/Tcn2/Mfge8/Ccn2/Lamp2/Pdgfa/Serpinb6c/Pdia3/Gdf3/Asah1/Ppt1/Ahnak/Apoc1/Selenos/Hspa4/Sema4b/Tsku/Lrp2/H2-D1/Lsr/Angptl4/Capg/Alad/Pdia4/Erbb3/Col7a1/Serpinb6a/Lamb1/Calr/Fabp5/Actg1/Cxadr/Aldoa/Fuca2/Dag1/Smpd1/Creg1/Cpn1/Cpxm1/Rab11a
GO:0030120 GO:0030120 vesicle coat 43 -0.6470973 -1.991571 0.0000493 0.0017462 0.0013435 1202 tags=40%, list=11%, signal=35% Copg2/Klhl12/Sec23a/Eps15/Sec13/Ap2s1/Copa/Aftph/Arcn1/Sec23b/Copb2/Copg1/Sec24d/Ap2a2/Pdcd6/Clta/Cltc
GO:0031461 GO:0031461 cullin-RING ubiquitin ligase complex 157 0.4706400 1.710861 0.0001149 0.0032943 0.0025345 1257 tags=20%, list=12%, signal=18% Fbxl20/Spopfm2/Ube2c/Pramel7/Tdpoz3/Tdpoz4/Pramel16/Skp2/Cks2/Kctd13/Cks1b/Vhl/Pramel38/Anapc7/Pramel48/Fbxo33/Pramel17/Cul5/Anapc11/Cdc20/Zswim5/Anapc16/Fbxo9/Fbxo31/Arih2/Fbxo15/Dcaf4/Ube2s/Klhl9/Amn1/Pramel5
GO:0009986 GO:0009986 cell surface 284 -0.3712475 -1.490994 0.0001944 0.0043541 0.0033499 2432 tags=37%, list=23%, signal=29% Lgals1/P4hb/Timd2/Il12rb1/Nectin2/Lamp1/H2-Ab1/Raet1a/Vsir/Bmpr1a/Anxa5/Plau/Dpp4/Clcn3/Cd59a/Atp5o/Jam2/Vamp3/Fgfr2/Slc9a1/Gm8909/Tyro3/H13/Lgals3/Phb2/Cd99l2/Atp5b/Tgfbr1/Msn/Eng/Lrp8/Nrg1/Egfl7/Anxa2/Aimp1/Gm12169/Itgb5/Arsa/Raet1e/B4galt1/Flot1/Ephb6/Apoe/Sdc4/Sdc1/Aamp/Insr/Ocln/Ctsl/Cd55/Epha4/Psen1/Tmx3/Fzd5/Clstn1/Atp6ap2/Arpc2/Adam15/H2-K1/Clic4/Sfrp1/Ly6a/Pdgfra/Dmd/Itgav/Sparc/Prom2/Lman2/Pecam1/Notch2/Tspan8/Cr1l/Got2/Krt18/Emp2/Erp44/Pebp1/Bace1/Mfge8/Pdgfa/Neu1/Pdia3/Usp14/Amot/Tmem102/Itga6/Lrp2/H2-D1/Pdia4/Atp5a1/Hspa5/Calr/Eno1b/Dppa1/Acvr1b/Cdh1/Ncl/Cd151/Dag1/Epcam/Eno1/Anxa4/Tjp2/Enpep/Plet1
GO:0043197 GO:0043197 dendritic spine 92 -0.4975503 -1.754027 0.0001972 0.0043541 0.0033499 1206 tags=23%, list=11%, signal=20% Mylk2/Arpc2/Add1/Atp2b1/Atp2b2/Comt/Ppp3ca/P2rx4/Cdc42/Ncoa2/Strn/Pten/Ppp1ca/Srgap2/Canx/Apbb1/Ppp1r2/Nedd4/Myo5b/Marcks/Igf2bp1
GO:0044309 GO:0044309 neuron spine 95 -0.4997056 -1.766404 0.0002025 0.0043541 0.0033499 1206 tags=23%, list=11%, signal=21% Mylk2/Arpc2/Add1/Atp2b1/Atp2b2/Comt/Slc9a6/Ppp3ca/P2rx4/Cdc42/Ncoa2/Strn/Pten/Ppp1ca/Srgap2/Canx/Apbb1/Ppp1r2/Nedd4/Myo5b/Marcks/Igf2bp1
GO:0005798 GO:0005798 Golgi-associated vesicle 60 -0.5436792 -1.773505 0.0004989 0.0088338 0.0067964 1856 tags=35%, list=17%, signal=29% Copb1/Zdhhc13/Actr1a/Tmed10/Copg2/Nucb1/Map6/Itm2b/Copa/Aftph/Arcn1/Copb2/Copg1/Tgoln1/Rab14/Smn1/Spg21/Kdelr1/Clta/Arf1/Cltc
GO:0042175 GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 430 -0.3321481 -1.394734 0.0005377 0.0092481 0.0071151 2093 tags=28%, list=20%, signal=24% Tyro3/H13/Syne3/Bsg/Dolk/Lnpk/Hacd2/Dgat2/Rtcb/Ncln/Ormdl2/Agpat3/Sel1l/Tram1/Acer3/Mia2/Serinc1/Tmem147/Saraf/Nploc4/Lmf1/Sec61a2/Slc35g1/Atf6/Yif1a/Rpn2/Calr4/Reep3/Selenok/Ergic3/Abhd12/Sc5d/Pigs/Ufl1/Gnai3/Cyb5r3/Abcb6/Psen1/Samd8/Plpp3/Tmx3/Atp13a1/Cant1/Wdr83os/Vti1b/Sec61a1/Pigz/Selenoi/Tap2/Pml/Stt3b/Yipf5/Cherp/Atp6ap2/Piga/H2-K1/Stt3a/Emc9/Emc2/Asph/Mogat2/Scd1/Magt1/Uba1/Sec23a/Stard3/Scd2/Rft1/Mboat1/Lman2/Hsd17b12/Tmbim6/Cyp4f39/Sptlc2/Slc9a6/Ier3ip1/Pigyl/Rab1a/Ddost/Erp44/Sptlc1/Elovl7/Slc35b3/Slc37a2/Sdf2l1/Lman1/Kdsr/Pdia3/Edem1/Stard3nl/Mia3/Selenos/Rab14/Sacm1l/Atf6b/Anxa7/Smpd4/Pik3r1/Tmco1/H2-D1/Eif5a/Rpn1/Kdelr1/Insig1/Abcd4/Wfs1/Elovl5/Canx/Hspa5/Calr/Tmem159/Slc35b1/Hsp90b1/Gpaa1/Rtn4/Xbp1/Ktn1/Ssr1/Vcp/Emc8/Spcs3
GO:0022626 GO:0022626 cytosolic ribosome 101 0.4974994 1.699674 0.0008145 0.0132529 0.0101964 2231 tags=40%, list=21%, signal=32% Larp4/Rpl7l1/Rplp0/Rpl39l/Rpl29/Rps3a1/Rps7/Rpl9/Rpl6/Rps24/Rpl17/Rps27l/Rpl41/Rpl11/Rpl13a/Rpl37rt/Rpl9-ps6/Rpl27/Rpl7a/Rps15a/Rpl28/D1Pas1/Rpl21/Rpl12/Rpl34/Rps14/Rpl23/Rps27/Rps17/Rps25/Rpl35/Rpl37/Rps3/Rpl24/Rpl32/Rps15/Rps21/Rpl18/Rps13/Rpl39
GO:0045178 GO:0045178 basal part of cell 124 -0.4388741 -1.611801 0.0010841 0.0157846 0.0121442 2630 tags=38%, list=25%, signal=29% Slc1a5/Slc4a2/Pkd1/Cadm1/Slc3a2/Ap2a1/Rab17/St14/Slc9a1/Abcc10/Slc7a1/Slc2a1/Tgfbr1/Msn/Anxa2/B4galt1/Atp12a/Flot1/Dsp/Atp1a1/Slc22a21/Slc39a14/Erbb2/Plpp3/Slc16a10/Slc6a13/Atp7b/Atp2b1/Slc23a2/Slc19a1/Tacstd2/Abcc1/Cr1l/Slc29a1/Slc16a1/Itga6/Ldlrap1/Ezr/Plec/Erbb3/Cdh1/Cxadr/Cldn4/Atp1b1/Dag1/Epcam/Epb41
GO:0005743 GO:0005743 mitochondrial inner membrane 358 -0.3260743 -1.337195 0.0018803 0.0221950 0.0170761 2276 tags=31%, list=21%, signal=25% Gpam/Ak2/Slc25a40/Slc25a30/Ndufa4/Mccc1/Abcb10/Prodh/Atp5o/Ndufb8/Opa1/Abcd3/Acadvl/Ndufb3/Cox5a/Mrpl17/Lgals3/Mpv17l2/Phb2/Afg3l2/Uqcr11/Slc25a22/Atp5b/Uqcrb/Maip1/Sdhc/Cibar1/Dmac2l/Ndufb9/Tmem177/Slc25a26/Smim20/Bdh1/Abcb7/Suclg1/Sdha/Pmpca/Spg7/Cyb5r3/Grpel1/Cpt2/Psen1/Dusp18/Atad3a/Crat/Cox6b1/Dnajc19/Ndufs1/Guf1/Letm1/Coq7/Stat3/Polg/Coq10b/Atp5j2/Acat1/Oxa1l/Ucp2/Ndufb11b/Mcur1/Fdx1/Ndufv1/Bcl2l1/Dmd/Cpt1a/Uqcrc2/Chchd10/Cox7a2l/Cox5b/Abcb8/Got2/Hadha/Lyn/Cox6a1/Coq5/Ndufs7/Ndufc2/Hmgcl/Tmem256/Cox7b/Sdhb/Cyc1/Hadhb/Atp5g3/Ndufa5/Cox4i1/Hsd17b10/Immt/Sco1/Atp5d/Ghitm/Fech/Srgap2/Tk2/Apool/Slc25a5/Atp5pb/Fdxr/Hadh/Slc25a13/Atp5a1/Ppif/Gcat/Parl/Uqcrc1/Uqcrfs1/Ndufa9/Vdac2/Slc25a4/Glud1/Acaa2
GO:0031252 GO:0031252 cell leading edge 250 -0.3544006 -1.404894 0.0024554 0.0268660 0.0206698 2027 tags=28%, list=19%, signal=23% Jcad/Gsn/Mapt/C2cd5/Myh9/Wwc1/Arhgef7/Arpc3/Fer/Bcar1/Nrg1/Anxa2/Itgb5/Flot1/Cdk6/Insr/Atn1/Caprin1/Arfip2/Pafah1b1/Iqgap1/Inpp5e/S100a11/Twf1/Arpc2/Raph1/Atp6v1b2/Kdf1/Vasp/Atp2b1/Sra1/Ssx2ip/Atp2b2/Tirap/Enah/Dmd/Itgav/Arhgef2/Mkln1/Epb41l5/Myo10/Pecam1/Dgkz/Ctnna1/Fscn1/Cdc42/Actr2/Coro1b/Carmil1/Amot/Inppl1/Cyth3/Pabpc1/Cd2ap/Srgap2/Ywhaz/Stxbp2/Ezr/Arpc5/Pdlim7/Tpm1/Eef1a1/Stx3/Apbb1/Cdh1/Dag1/Frmd4b/Arf1/Actr3/Rdx
GO:0098794 GO:0098794 postsynapse 274 -0.3473151 -1.394872 0.0031762 0.0315098 0.0242426 1224 tags=17%, list=11%, signal=16% Clstn1/Atp6ap2/Mylk2/Arpc2/Add1/Cpeb4/Pdlim5/Atp2b1/Atp2b2/Vps35/Dmd/Arhgef2/Comt/Pfn2/Ppp3ca/Lyn/P2rx4/Cdc42/Actr2/Ncoa2/Strn/Epb41l1/Nck2/Mettl5/Pten/Sema4b/Ppp1ca/Sigmar1/Srgap2/Ywhaz/Pick1/Efnb2/Erbb3/Nsf/Canx/Stx3/Apbb1/Fabp5/Dag1/Rtn4/Ppp1r2/Nedd4/Clta/Rab11a/Myo5b/Marcks/Igf2bp1
GO:0042555 GO:0042555 MCM complex 11 -0.7817380 -1.744793 0.0031814 0.0315098 0.0242426 1006 tags=45%, list=9%, signal=41% Mcm3/Mcm5/Mcm8/Mcm4/Mcm6
GO:0061695 GO:0061695 transferase complex, transferring phosphorus-containing groups 209 0.3936136 1.491848 0.0032218 0.0315098 0.0242426 1381 tags=22%, list=13%, signal=20% Ccnb1/Cdk1/Taf13/Atg14/Cks2/Polr2j/Socs3/Cks1b/Amhr2/Pole4/Rprd1b/Polr2h/Taf7/Cdkn1a/Polr3a/Prps1/Cdkn2d/Polr1h/Rprd1a/Cdk2/Polrmt/Polr3h/Ccny/Supt3/Prim1/Brd4/Rb1cc1/Pold1/Becn2/Smcr8/Polr2b/Prpsap1/Pold3/Taf8/Prkar1a/Gtf2h5/Polr1c/Rpap2/Myo6/Polr1d/Gtf2h4/Polr3f/Gtf2h1/Taf12/Gtf2f2/Kat2a/Polr2d
GO:0098858 GO:0098858 actin-based cell projection 110 -0.4325412 -1.567854 0.0034702 0.0316525 0.0243523 1442 tags=25%, list=14%, signal=21% Ctsl/Pafah1b1/Epha4/Erbb2/Atp6v1a/Slc9a3r1/Dcxr/Twf1/Atp6v1b2/Clic4/Vasp/Pdgfra/Enah/Dmd/Itgav/Myo10/Prom2/Fscn1/Cdc42/Acpp/Pdgfa/Ezr/Apbb1/Cxadr/Dag1/Nedd4/Rdx
GO:0005903 GO:0005903 brush border 75 -0.4657252 -1.595823 0.0036277 0.0322619 0.0248212 2256 tags=39%, list=21%, signal=31% Pex19/Myh10/Itpr3/Amn/Myh9/Dnm1l/Slc28a3/B4galt1/Gipc1/Slc22a21/Add3/Lct/Slc6a14/Trpm6/Ralgds/Lctl/Slc9a3r1/Dcxr/Slc19a1/Flnb/Gna13/Capza2/Lrp2/Ezr/Plec/Cgn/Actr3/Myo5b/Enpep
GO:0000940 GO:0000940 outer kinetochore 13 0.7729575 1.773684 0.0036442 0.0322619 0.0248212 1501 tags=46%, list=14%, signal=40% Ccnb1/Plk1/Cenpe/Ndc80/Ska2/Ska3
GO:0046930 GO:0046930 pore complex 14 -0.7246426 -1.728972 0.0047303 0.0369820 0.0284526 292 tags=36%, list=3%, signal=35% Spg7/Slc25a5/Ppif/Vdac2/Slc25a4
GO:0005771 GO:0005771 multivesicular body 33 -0.5721529 -1.669527 0.0061236 0.0438861 0.0337644 1690 tags=55%, list=16%, signal=46% Steap3/H2-DMb2/Chmp6/Ctsl/Abcb6/Chmp4c/Chmp2b/Cst3/Chmp3/Laptm4b/Chmp1a/Acpp/Bace1/Chmp1b/Tmem9/Vta1/Gja1/Rab11a
dead vs ctrl - Biological Process GO
ID Description setSize enrichmentScore NES pvalue p.adjust qvalues rank leading_edge core_enrichment
GO:0006066 GO:0006066 alcohol metabolic process 183 -0.5023948 -2.017436 0.0000000 0.0000730 0.0000695 2156 tags=38%, list=20%, signal=31% Akr1c14/Srebf2/Impa2/Dhcr7/Sptlc2/Gba2/Acpp/Sod1/Pten/Ip6k2/Galk1/Park7/Akr1b3/Slc37a2/Gde1/Por/Acer1/Tsku/Rdh11/Ldlrap1/Inpp5k/Tpi1/Srebf1/Nfe2l1/Msmo1/Insig1/Clcn2/Sgpp1/Sptlc1/Fdft1/Ocrl/Fdxr/Mvd/Inpp5b/Spr/Aco2/Hdlbp/Prkaa2/Smpd1/Qdpr/Cyb5r3/Lpcat3/Nsdhl/Lbr/Mogat2/Dab2/Cyp51/Acadvl/Plcb3/Ldlr/Pgp/Arv1/Aplp2/Got1/Pmvk/Sc5d/Ppip5k2/Fdx1/Dpm1/Isyna1/Fdps/Lss/Asah1/Idh1/Hmgcs1/Idh3a/Akr1b8/Sqle/Hmgcr
GO:0043648 GO:0043648 dicarboxylic acid metabolic process 59 -0.6506762 -2.196548 0.0000002 0.0003864 0.0003680 1417 tags=42%, list=13%, signal=37% Nit2/Kyat3/Me2/Acot8/Aldh4a1/Aldh18a1/Grhpr/Mdh2/Gclm/Mdh1/Sdhb/Dlst/Ass1/Got1/Shmt2/Dld/Suclg1/Fh1/Sdha/Acly/Glud1/Idh1/Idh3a/Cs/Sucla2
GO:0045216 GO:0045216 cell-cell junction organization 99 -0.5594854 -2.057169 0.0000003 0.0003864 0.0003680 1475 tags=28%, list=14%, signal=25% Pkn2/Vcl/Dsg2/Pkp2/Rdx/Dlg1/Pdcd6ip/Marveld3/Cxadr/Numbl/Rhoa/Cdc42/Actn4/Lims2/Ctnnb1/Cldn6/Efnb2/Pak2/Lsr/Actb/Rac1/Tjp2/Itgb1/Cdh1/Wdr1/Actg1/F11r/Gja1
GO:0006099 GO:0006099 tricarboxylic acid cycle 28 -0.7676160 -2.252756 0.0000012 0.0011687 0.0011131 940 tags=50%, list=9%, signal=46% Mdh2/Dlat/Mdh1/Aco2/Sdhb/Dlst/Sdhd/Suclg1/Fh1/Sdha/Idh1/Idh3a/Cs/Sucla2
GO:0006694 GO:0006694 steroid biosynthetic process 76 -0.5707679 -2.007467 0.0000046 0.0021450 0.0020430 1505 tags=36%, list=14%, signal=31% Por/Cyb5r1/Hint2/Srebf1/Msmo1/Insig1/Clcn2/Fdft1/Mvd/Prkaa2/Stard4/Ddx20/Cyb5r3/Lpcat3/Nsdhl/Lbr/Dab2/Cyp51/Pmvk/Sc5d/Fdx1/Fdps/Lss/Asah1/Hmgcs1/Sqle/Hmgcr
GO:0006790 GO:0006790 sulfur compound metabolic process 180 -0.4401857 -1.763406 0.0000078 0.0031897 0.0030381 1327 tags=24%, list=12%, signal=21% Nubp2/Mtap/Gpam/Nubp1/Glce/Gstp1/Nfe2l1/Acot8/Sult4a1/Acsl3/Dlat/Gclm/Dnmt1/Acaa2/Slc1a1/Mvd/Arl6ip5/Hmgcl/Glo1/Ptges2/Nfu1/Blmh/Nfe2l2/Comt/Gstp2/Gss/Isca1/Csad/Pmvk/Sod2/Dld/Chpf/Ahcyl/Suclg1/Gsr/Acly/Hspa9/Ciapin1/Idh1/Hmgcs1/Ahcy/Cs/Sucla2
GO:0002181 GO:0002181 cytoplasmic translation 89 0.5519693 1.944532 0.0000090 0.0031897 0.0030381 2041 tags=45%, list=19%, signal=37% Rpl9/Rpl41/Rpl24/Rpl18/Rpl6/Rpl11/Rpl10a/Eif5/Dph3/Rplp0/Rpl17/Rpl29/Rpl15/Rplp1/Rpl32/Ftsj1/Eif2b3/Rpl26/Rpl31/Cnbp/Drg2/Dhx36/Rpl19/Rpl39/Rpl9-ps6/Rps21/Rplp2/Drg1/Rpl35a/Eif3i/Dph5/Rps23/Rwdd1/Rpl22l1/Rpl18a/Rps26/Rpl36/Rpl36al/Rpl38/Eif4h
GO:0071407 GO:0071407 cellular response to organic cyclic compound 235 -0.4066426 -1.664625 0.0000197 0.0057670 0.0054928 1768 tags=31%, list=17%, signal=27% Ehmt2/Ywhah/Tfap4/Ppp5c/Pdia3/Daxx/Tmem38b/Ncoa2/Casp9/Rnf14/Snw1/Foxh1/Casp7/Mgarp/Slc9a3r1/Ssh1/Ufl1/Fancb/Pde12/Stat3/Parp1/Rnf6/Adcy3/Inpp5k/Nfe2l1/Cry1/Dnm1l/Mul1/Btrc/Gabpa/Insig1/Blm/Brca1/Rhoa/Yap1/Mapk1/Ncstn/Akt2/Vps35/Epg5/Cnot9/Slc1a1/Hnrnpk/Flot1/Ube2l3/Arl6ip5/Smyd3/Sirt2/Phb/Pak4/Ranbp1/Msx2/Gnai3/Nos1/Dab2/Ralb/Pias2/Nedd4/Gna11/Arpc2/Calcoco1/Ctnnb1/Wbp2/Fdx1/Zc3hav1/Uba5/Pak2/Calr/Actb/Glrx/Prmt5/Hsp90b1/Cdh1/P2rx3
GO:0022613 GO:0022613 ribonucleoprotein complex biogenesis 392 0.3678743 1.534979 0.0000354 0.0094885 0.0090373 2122 tags=31%, list=20%, signal=25% Rpl3/Pa2g4/Eif6/Rpf1/Ago1/Rpl24/Rpp25/Exosc5/Rpl10l/Rpl6/Rpl11/Emg1/Rpl5/Rpl10a/Rpl7/Eif5/Rpp38/Rplp0/Dimt1/Mrto4/Rps6/Crnkl1/C1qbp/Helq/Rps7/Kri1/Ruvbl1/Rpl7a/Rps24/Znhit3/Fcf1/Rpp30/Rpl7l1/Rps25/Gtf2h5/Mrpl20/Exosc1/Wdr75/Rps16/Rps15/Pop5/Clns1a/Rsl24d1/Exosc7/Mettl16/Celf3/Rpl26/Krr1/Rps19/Nop10/Tent4b/Rpl27/Rpl35/Mettl5/Tarbp2/Riox2/Lsm2/Gemin2/Rps27l/Trmt112/Npm1/Ptges3/Exosc8/Srpk1/Ramac/Scaf11/Ago3/Isg20l2/Rps21/Mrpl22/Snu13/Surf6/Nhp2/Rps17/Gnl2/C1d/Eral1/Snrpe/Mrps7/Snrpc/Rbis/Rpf2/Rps14/Rpl35a/Polr2d/Rcl1/Ncbp1/Wdr43/Esf1/Rbfa/Setx/Rps8/Nob1/Frg1/Tsc1/Mdn1/Zcchc4/Gnl3l/Riok1/Mybbp1a/Snrpb/Aatf/Dcaf13/Rps5/Utp20/Ythdc1/Rpl38/Nop58/Urb1/Nop53/LTO1/Eif4h/Ddx54/Luc7l2/Zrsr1/Drosha/Snrpd1/Celf1/Tsr2/Sf3a2
GO:0030036 GO:0030036 actin cytoskeleton organization 410 -0.3384133 -1.469045 0.0000513 0.0100084 0.0095325 1569 tags=20%, list=15%, signal=18% Mphosph8/Pdlim5/Actr2/Pik3r1/Whamm/Marcksl1/Myo5b/Slc9a3r1/Pstpip2/Ssh1/Add3/Myh10/Trim27/Myh9/Vill/Pdgfra/Inpp5k/Pick1/Mlst8/Rdx/Epb41l1/Dlg1/Pdcd6ip/Cxadr/Phldb2/Shc1/Capg/Setd3/Tle6/Tmsb10/Rhoa/Strip1/Coro1b/Ppm1f/Atp2c1/Coro1c/Flii/Kiss1r/Cdk10/Carmil1/Cdc42/Prr5/Arf1/Trim32/Rflnb/Tpm1/Swap70/Wasf2/Arhgdia/Sdcbp/Actn4/Tpm4/Rnd2/Emp2/Arpc2/Bag4/Marcks/Ilk/Nisch/Krt8/Epb41/Epb41l5/Pak2/Rnd3/Calr/Cap1/Actb/Rac1/Tmod3/Capzb/Actr3/Capn10/Cttn/Myo1e/Itgb1/Hsp90b1/Khdc3/Cdh1/Wdr1/Actg1/F11r/Cdc42ep5
GO:0030029 GO:0030029 actin filament-based process 443 -0.3321307 -1.453583 0.0000576 0.0107912 0.0102781 1569 tags=20%, list=15%, signal=18% Mphosph8/Pdlim5/Actr2/Pik3r1/Whamm/Marcksl1/Myo5b/Slc9a3r1/Pstpip2/Ssh1/Add3/Myh10/Trim27/Myh9/Nup155/Vill/Pdgfra/Inpp5k/Dsg2/Pick1/Pkp2/Mlst8/Rdx/Epb41l1/Dlg1/Pdcd6ip/Srgap2/Cxadr/Phldb2/Shc1/Capg/Setd3/Tle6/Tmsb10/Rhoa/Strip1/Coro1b/Ppm1f/Atp2c1/Coro1c/Flii/Kiss1r/Cdk10/Carmil1/Cdc42/Prr5/Arf1/Trim32/Rflnb/Tpm1/Swap70/Wasf2/Arhgdia/Nos1/Sdcbp/Actn4/Tpm4/Rnd2/Camk2d/Emp2/Arpc2/Bag4/Marcks/Ilk/Nisch/Krt8/Epb41/Epb41l5/Pak2/Rnd3/Calr/Cap1/Actb/Rac1/Tmod3/Capzb/Actr3/Capn10/Cttn/Myo1e/Itgb1/Hsp90b1/Khdc3/Cdh1/Wdr1/Actg1/F11r/Cdc42ep5
GO:0071260 GO:0071260 cellular response to mechanical stimulus 17 -0.7986996 -2.088395 0.0000731 0.0125598 0.0119625 561 tags=41%, list=5%, signal=39% Arhgdia/Nos1/Got1/Ctnnb1/Rac1/F11r/Dag1
GO:0044283 GO:0044283 small molecule biosynthetic process 315 -0.3587605 -1.519133 0.0000750 0.0125598 0.0119625 1239 tags=23%, list=12%, signal=21% Tpi1/Srebf1/Gstp1/Cry1/Psat1/Acsl3/Msmo1/Gulo/Insig1/Gpi1/Brca1/Clcn2/Aldh18a1/Slc35b4/Sptlc1/Pgd/Fdft1/Hacd2/Maea/Cyp2c23/Prkag1/Fads1/Fdxr/Mvd/Supt20/Elovl5/Adk/Ptges/Ddb1/Spr/Coq10b/Slc39a14/Hmgcl/Prkaa2/Mid1ip1/Acsbg1/Elovl7/Stard4/Lpgat1/Ass1/Qdpr/Ptges2/Cyb5r3/Lpcat3/Nsdhl/Lbr/Dab2/Cyp51/Gstp2/Acadvl/Csad/Pgp/Aldoa/Got1/Pmvk/Sc5d/Srr/Ppip5k2/Pycr2/Gapdh/Shmt2/Coq9/Rgn/Scd1/Acly/Isyna1/Fdps/Lss/Asah1/Pkm/Scd2/Hmgcs1/Hmgcr
GO:0034976 GO:0034976 response to endoplasmic reticulum stress 200 -0.4078825 -1.657700 0.0000853 0.0133261 0.0126923 1865 tags=30%, list=18%, signal=25% Wfs1/Park7/Trp53/Fbxo44/Pdia3/Eif2b5/Qrich1/Casp9/Psmc6/Rnf5/Pik3r1/Marchf6/Ppp2cb/Nrbf2/Tmbim6/Ufl1/Dnajc10/Tmtc4/Ube4a/Tmx1/Pla2g6/Manf/Tmem259/Erp44/Tmtc3/Syvn1/Nfe2l1/Trim25/Nploc4/Ikbkg/Hyou1/Fbxo6/Flot1/Fbxo2/Svip/Lpcat3/Faf2/Cops5/Ubxn4/Stt3b/Nfe2l2/Atf6b/Vcp/Erp29/Ccdc47/Selenok/Ermp1/Uba5/Calr/Ubqln1/Hspa5/Pdia6/Usp19/Sdf2l1/Canx/Hsp90b1/Foxred2/P4hb/Aifm1/Pdia4
GO:0071467 GO:0071467 cellular response to pH 10 -0.8664118 -1.943502 0.0001132 0.0165721 0.0157840 422 tags=30%, list=4%, signal=29% Gna11/Hvcn1/Gja1
GO:0044282 GO:0044282 small molecule catabolic process 198 -0.3969935 -1.613423 0.0001905 0.0250086 0.0238193 2219 tags=34%, list=21%, signal=27% Dbi/Dera/Got2/Pnp/Impa2/Hadh/Haghl/Faah/Tat/Scly/Pten/Galk1/Park7/Echdc1/Ldha/Trp53/Acaa1a/Eci2/Mgat1/Amdhd2/Nagk/Bckdk/Pex5/Hadha/Pfkp/Pfkl/Inpp5k/Tpi1/Acat2/Acot8/Urah/Pex13/Gpi1/Crat/Aldh4a1/Etfb/Pgd/Ocrl/Akt2/Acaa2/Inpp5b/Hmgcl/Echs1/Glo1/Foxk1/Qdpr/Acox1/Blmh/Nos1/Acadvl/Csad/Slc27a4/Got1/Pfkfb2/Eno1b/Nudt5/Etfa/Eno1/Shmt2/Ahcyl/Hadhb/Glud1/Khk/Upp1/Mfsd2a/Ahcy/Akr1b8
GO:0150105 GO:0150105 protein localization to cell-cell junction 22 -0.7144597 -1.965949 0.0002454 0.0294886 0.0280862 511 tags=32%, list=5%, signal=30% Actn4/Pak2/Lsr/Actb/Tjp2/Actg1/F11r
GO:0022604 GO:0022604 regulation of cell morphogenesis 209 -0.3862482 -1.567668 0.0002844 0.0325096 0.0309636 1486 tags=22%, list=14%, signal=20% Myo5b/Slc9a3r1/Rreb1/Myh10/Myh9/Slc26a5/Rdx/Dlg1/Dnm1l/Mul1/Rcc2/Myl12b/Myl12a/Numbl/Rhoa/Strip1/Coro1b/Hnrnpk/Coro1c/Xlr3b/Carmil1/Cdc42/Anxa7/Tpm1/Arhgdia/Dab2/Actn4/Kalrn/Anapc2/Rnd2/Aldoa/Pias2/Arpc2/Lims2/Marcks/Ilk/Epb41/Rnd3/Calr/Rac1/Capzb/Actr3/Mfsd2a/P4hb/Wdr1/F11r/Cdc42ep5
GO:0040017 GO:0040017 positive regulation of locomotion 289 -0.3501893 -1.473454 0.0002928 0.0326632 0.0311099 1459 tags=24%, list=14%, signal=21% Ssh1/Rreb1/Stat3/Fam83h/Hmox1/Rab11a/Pdgfra/Trip6/Slc26a5/Rdx/Map2k1/Akap12/Mapk8ip3/Stx3/Dnm1l/Bsg/Gpi1/Rras2/Rhoa/Atp5b/Mapk1/Elp3/Akt2/Ppm1f/Vps35/Akirin1/Tmem102/Mpzl1/Carmil1/Hspb1/Sema3b/Plau/Prr5/Map2k3/Trim32/Lyn/Map3k3/Prkd2/Swap70/Atp8a1/Nfe2l2/Sdcbp/Dab2/Actn4/Aldoa/Camk2d/Emc10/Jam2/Arpc2/Bag4/Ilk/Selenok/Epcam/Sod2/Acvr1b/Epb41l5/Calr/Rac1/Actr3/Spi1/Hspa5/Cttn/Atp5a1/Ptp4a1/Itgb1/Lamb1/Plet1/Actg1
GO:1903827 GO:1903827 regulation of cellular protein localization 377 -0.3325958 -1.433456 0.0003404 0.0370992 0.0353350 1534 tags=21%, list=14%, signal=19% Pik3r1/Asph/Myo5b/Ssh1/Plk3/Rab29/Ric3/Parp1/Ldlrap1/Rab11a/Inpp5k/Mapt/Cct8/Rdx/Parl/Map2k1/Srebf1/Kat7/Vti1b/Dlg1/Stx3/Nucb1/Acsl3/Atpif1/Hnrnpm/Gdi1/Insig1/Csnk2a1/Pin1/Brca1/Yap1/Mapk1/Cct4/Akt2/Ppm1f/Atp2c1/Vps35/Cct5/Slc1a1/Hnrnpk/Pdcd5/Svip/Tcp1/Tmbim1/Cdc42/Prkaa2/Cct2/Cct3/Cnpy4/Uaca/Anp32b/Tax1bp3/Rangap1/Dab2/Kalrn/Ralb/Camk2d/Maged1/Vcp/Arpc2/Bag4/Ctnnb1/Wapl/Epb41/Actb/Tmem30a/Actr3/Tsg101/Zfand1/Spi1/Oaz2/Macroh2a1/Leprot/Itgb1/Sqstm1/Ap2m1/Cdh1/Cltc/Dag1
GO:0022618 GO:0022618 ribonucleoprotein complex assembly 159 0.4259066 1.623773 0.0004194 0.0436384 0.0415632 2456 tags=36%, list=23%, signal=28% Rpl3/Eif6/Ago1/Rpl24/Rpl10l/Rpl6/Rpl11/Rpl5/Eif5/Rplp0/Mrto4/Crnkl1/Ruvbl1/Znhit3/Rps25/Mrpl20/Rps15/Clns1a/Celf3/Rps19/Tarbp2/Lsm2/Gemin2/Rps27l/Ptges3/Srpk1/Ramac/Scaf11/Ago3/Snu13/Eral1/Snrpe/Mrps7/Snrpc/Rpf2/Rps14/Polr2d/Ncbp1/Setx/Mdn1/Snrpb/Rps5/Ythdc1/Rpl38/Nop53/Eif4h/Luc7l2/Zrsr1/Snrpd1/Celf1/Sf3a2/Cpsf7/Pwp2/Mcts1/Rpl10/Srpk2/Rps27/Nufip1
GO:0036503 GO:0036503 ERAD pathway 92 -0.4615265 -1.689095 0.0004240 0.0436384 0.0415632 1563 tags=27%, list=15%, signal=23% Psmc6/Rnf5/Marchf6/Dnajc10/Ube4a/Tmem259/Syvn1/Trim25/Nploc4/Fbxo6/Fbxo2/Svip/Faf2/Ubxn4/Stt3b/Vcp/Ccdc47/Calr/Ubqln1/Hspa5/Usp19/Sdf2l1/Canx/Hsp90b1/Foxred2
dead vs ctrl - Molecular Function GO
ID Description setSize enrichmentScore NES pvalue p.adjust qvalues rank leading_edge core_enrichment
GO:0003735 GO:0003735 structural constituent of ribosome 158 0.6950580 2.675596 0.00e+00 0.0000001 0.0000001 1964 tags=58%, list=18%, signal=48% Rpl3/Mrpl27/Mrps6/Rpl9/Rpl41/Rpl12/Rpl24/Rps3a1/Rps9/Gm2000/Rpl18/Rpl10l/Rpl6/Rpl11/Rpl5/Rpl21/Rpl10a/Rpl7/Rplp0/Mrpl16/Rpl17/Rpl29/Rpl15/Rps6/Rps15a/Rps13/Rps27a/Mrps21/Mrpl21/Rps7/Rpl13/Rps18/Rpl7a/Rps24/Mrps18a/Rplp1/Rpl7l1/Rps10/Rps12/Rpl32/Rps25/Mrpl20/Rps16/Rps15/Mrps30/Rsl24d1/Mrpl34/Rps20/Mrps14/Rpl34/Rpl26/Rpl31/Mrpl47/Rps19/Rpl27/Rpl35/Rps4x/Rpl37a/Mrps17/Mrpl12/Rps3/Rps27l/Mrpl3/Rpl19/Rpl39/Rpl9-ps6/Mrpl32/Rpl27a/Rps21/Mrps15/Mrpl22/Fau/Rplp2/Rps17/Rpl23/Mrpl46/Mrps7/Mrps18c/Rps14/Rpl35a/Rps23/Rpl22l1/Rpl18a/Rps8/Rps26/Mrpl14/Rpl36/Rps5/Rpl36al/Rps11/Mrpl41/Rpl38
GO:0019843 GO:0019843 rRNA binding 72 0.6517625 2.250827 0.00e+00 0.0000072 0.0000065 1492 tags=43%, list=14%, signal=37% Rpl3/Mrps6/Rpl9/Rpf1/Rpl12/Rps9/Rpl6/Rpl11/Emg1/Rpl5/Kdm2b/Rpl7/Rplp0/Mrpl16/Rpl17/Rps13/Rps18/Mrps18a/Mrpl20/Rps4x/Rpl37a/Mrps17/Rps3/Npm1/Rpl19/Rpl23/Eral1/Mrps7/Mrps18c/Rpf2/Rps14
GO:0016491 GO:0016491 oxidoreductase activity 414 -0.3805684 -1.667822 3.00e-07 0.0000748 0.0000672 2156 tags=30%, list=20%, signal=25% Akr1c14/Blvra/Mthfd2/Coq7/Coil/Sesn1/Pdha1/Ifi30/Hadh/Dhcr7/Gsta4/Fads2/Txnl1/Cyp2f2/Me1/Sod1/Ethe1/Hspbap1/Kdm3b/Park7/Far1/D2hgdh/Akr1b3/Ldha/Acaa1a/Ogfod3/Pdia3/Steap1/Acad9/Dcxr/Pgk1/Vat1/Tet2/Hsdl2/Asph/Por/Cyb5r1/Dnajc10/Rdh11/Hadha/Tmx1/Cyb5a/Hmox1/Blvrb/Me2/Gstp1/Glyr1/Cyb561d2/Ptgr2/Msmo1/Gulo/Crat/Aldh4a1/Etfb/Aldh18a1/Rrm2/Grhpr/Cyc1/Qsox1/Pgd/Mdh2/Cox6a1/Dlat/Selenof/Cyp2c23/Gclm/Fads1/Fdxr/Dus2/Mdh1/Pdia5/Ptges/Spr/Cyct/Sdhb/Sccpdh/Uevld/Txnrd1/Qdpr/Ptges2/Acox1/Cyb5r3/Jmjd7/Nsdhl/Ndufv1/Gpx2/Lbr/Nos1/Cyp51/Gstp2/Kdm6b/Loxhd1/Acadvl/Aldh2/Rrm1/Sc5d/Etfa/Sdhd/Fdx1/Steap3/Pycr2/Ndufs1/Sod2/Gapdh/Dld/Plod1/Kdm2a/Gsr/Scd1/Glrx/Sdha/Glud1/Pdia6/Prdx2/Scd2/Aldh1b1/Idh1/Idh3a/Foxred2/Prdx1/P4hb/Akr1b8/Sqle/Aifm1/Pdia4/Hmgcr
GO:0016874 GO:0016874 ligase activity 134 -0.4610021 -1.807232 1.95e-05 0.0029379 0.0026383 2005 tags=33%, list=19%, signal=27% Yars2/Rars/Mars2/Aasdh/Lig1/Rimkla/Aars/Vars/Ears2/Tars2/Ctps/Rars2/Kars/Gmps/Ghdc/Yars/Ifnar1/Atp5o/Trim25/Acsl3/Lig4/Ctps2/Atp6v1a/Dars/Atp5b/Uba3/Gclm/Farsb/Farsa/Acsbg1/Mars1/Dars2/Ass1/Gars/Gss/Slc27a4/Uba5/Suclg1/Atp5a1/Uchl1/Lig3/Nars/Vars2/Sucla2
GO:0050660 GO:0050660 flavin adenine dinucleotide binding 55 -0.5967255 -2.018453 2.16e-05 0.0029379 0.0026383 1829 tags=38%, list=17%, signal=32% D2hgdh/Acad9/Mto1/Por/Cyb5r1/Cry1/Gulo/Qsox1/Dus2/Txnrd1/Acox1/Cyb5r3/Nos1/Acadvl/Etfa/Dld/Gsr/Sdha/Foxred2/Sqle/Aifm1
GO:0016462 GO:0016462 pyrophosphatase activity 397 -0.3489469 -1.522412 3.99e-05 0.0046545 0.0041798 1914 tags=26%, list=18%, signal=22% Abcc10/Gng2/Gfm2/Yme1l1/Hspd1/Mras/Rab24/Gpn1/Rad54l2/Efl1/Rab18/Dqx1/Mlh1/Dxo/Rab6a/Nvl/Tufm/Vps4b/Nudt14/Hsp90ab1/Pms2/Psmc6/Ide/Myo5b/Slc25a42/Stard9/Rab29/Gmps/Rab40c/Nubp2/Rab11a/Nubp1/Atp5o/Cct8/Hbs1l/Tuba4a/Dnm1l/Bms1/Hyou1/Atad1/Septin7/Tubb2b/Tubg1/Rras2/Rhoa/Atp5b/Cct4/Rfc4/Kif21b/Clpb/Cct5/Prune1/Tcp1/Rap2c/Tuba1c/Rab4a/Rab1a/Cdc42/Septin2/Rragd/Cct2/Cct3/Psmc3/Nsf/Fignl1/Rab2a/Gnai3/Gfm1/Abcb10/Nudt12/Abcb8/Gars/Atp13a1/Dcps/Ralb/Psmc2/Spg7/Rnd2/Psmc1/Lsg1/Gna11/Rfc2/Vcp/Tubb2a/Septin11/Psmc4/Nudt5/Abce1/Rnd3/Srpr/Rac1/Rab1b/Abcf3/Tubb5/Nkiras2/Hspa5/Hspa9/Atp5a1/Tuba1a/Hsp90b1/Eef1a1/Psmc5/Tuba1b
dead vs ctrl - Cellular Component GO
ID Description setSize enrichmentScore NES pvalue p.adjust qvalues rank leading_edge core_enrichment
GO:0043209 GO:0043209 myelin sheath 160 -0.5980439 -2.364987 0.0000000 0.0000000 0.0000000 1253 tags=39%, list=12%, signal=35% Atp5o/Rdx/Dlg1/Pdcd6ip/Atp6v1a/Ehd1/Gdi1/Septin7/Gpi1/Atp5b/Ubb/Mdh2/Cox6a1/Dlat/Cct5/Mdh1/Tcp1/Aco2/Cdc42/Immt/Septin2/Sirt2/Phb/Dlst/Cct2/Cct3/Ass1/Nsf/Tkt/Atp1b1/Aldoa/Ubc/Vcp/Slc25a5/Uqcrc2/Eno1/Ndufs1/Sod2/Gapdh/Dld/Actb/Sdha/Hspa5/Hspa9/Slc25a4/Canx/Atp5a1/Uchl1/Tuba1a/Pkm/Itgb1/Prdx2/Uqcrc1/Eef1a1/Idh3a/Vdac2/Prdx1/Cdh1/Wdr1/Actg1/Cltc/Sucla2/Tuba1b
GO:0042175 GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 430 -0.3818714 -1.666538 0.0000000 0.0000026 0.0000021 2103 tags=29%, list=20%, signal=24% Ankle2/Ssr1/Rtn4/Dhcr7/Sptlc2/Tmem258/Gba2/Bscl2/Tmem39a/Xbp1/Wdr83os/Ddost/Myorg/Sgms1/Wfs1/Slc35g1/Lrrc8e/Slc37a2/Reep4/Pdia3/Pomt1/Mia3/Lman1/Nup62/Ormdl2/Pigz/Pik3r1/Marchf6/Asph/Tmbim6/Ufl1/Rdh11/Pigs/Lmf2/Tmx1/Smpd4/Cyb5a/Erp44/Dolk/Eif5a/Eda/Syvn1/Nfe2l1/Vti1b/Nploc4/Stt3a/Bsg/Msmo1/Esyt1/Sacm1l/Insig1/Yif1b/Sgpp1/Slc9a6/Slc35b4/Sptlc1/Rtn3/Rpn1/Fdft1/Hacd2/Cyp2c23/Pigu/Yipf5/Pigq/Rft1/Elovl5/Svip/Ndrg4/Rab1a/Anxa7/Cept1/Elovl7/Lpgat1/Emc8/Tmem41b/Gpaa1/Cyb5r3/Kdelr2/Pld3/Rab2a/Gnai3/Lpcat3/Esyt3/Faf2/Lbr/Mogat2/Stt3b/Nos1/Atp13a1/Ptdss1/Tkt/Atf6b/Arv1/Slc27a4/Emc10/Sppl2b/Vcp/Ccdc47/Sc5d/Lmbr1l/Selenok/Tex264/Dpm1/Uba5/Abhd12/Slc35b1/Ktn1/Calr/Srpr/H2-K1/Vapa/Scd1/Hspa5/Usp19/Preb/Srprb/Sdf2l1/Lss/Canx/Scd2/Sec61a1/Hsp90b1/Tmem159/Hmgcr/Selenoi
GO:0005911 GO:0005911 cell-cell junction 250 -0.4364032 -1.822906 0.0000005 0.0000232 0.0000188 1780 tags=27%, list=17%, signal=23% Akr1b3/Sympk/Slc2a1/Ywhah/Actn1/Patj/Pdlim4/Pdlim5/Pik3r1/Pkn2/Add3/Vcl/Ccdc85b/Myh9/B4galt1/Cyth2/Dsg2/Pkp2/Gjb5/Aqp3/Dlg1/Stx3/Pdcd6ip/Marveld3/Cxadr/Frmd4b/Tnks1bp1/Rhoa/Clic4/Nectin2/Flot1/Rap2c/Cdc42/Sirt2/Lyn/Gjb3/Ppp1ca/Traf4/Strn/Wasf2/Actn4/Atp1b1/Camk2d/Sdccag8/Jam2/Lims2/Ilk/Ctnnb1/Cldn6/Epcam/Krt8/Epb41l5/Pak2/Lsr/Actb/Vapa/Capzb/Actr3/Tjp2/Keap1/Myo1e/Itgb1/Cdh1/Wdr1/Actg1/F11r/Gja1/Dag1
GO:0005938 GO:0005938 cell cortex 184 -0.4604429 -1.850019 0.0000005 0.0000254 0.0000205 1758 tags=28%, list=16%, signal=24% Slc2a1/Agtrap/Actn1/Fgfr2/Daxx/Pfn1/Actr1a/Actr2/Anxa2/Asph/Myo5b/Add3/Exoc8/Myh10/Myh9/Rdx/Map2k1/Myl12b/Septin7/Phldb2/Tle6/Rhoa/Maea/Akt2/Hnrnpk/Flot1/Septin2/Actn4/Tpm4/Rnd2/Arv1/Nedd4/Marcks/Septin11/Eno1b/Ctnnb1/Eno1/Epb41/Rnd3/Cap1/Actb/Rac1/Capzb/Capn10/Mpp1/Cttn/Myo1e/Eef1a1/Khdc3/Cdh1/Wdr1
GO:0005844 GO:0005844 polysome 68 0.5899550 2.001390 0.0000062 0.0002236 0.0001806 2016 tags=53%, list=19%, signal=43% Rpl41/Epm2a/Ago1/Rpl24/Rpl18/Rpl10l/Rpl6/Rpl11/Rpl10a/Rpl7/Larp4/Rpl17/Rpl29/Rps6/Rpl7a/Rpl32/Rps25/Psma6/Rpl31/Rps4x/Nufip2/Rps3/Rpl19/Rpl39/Eif2ak4/Rps21/Drg1/Rps23/Rwdd1/Rpl18a/Rps26/Rpl36/Rpl36al/Gcn1/Rpl38/Btf3
GO:0044309 GO:0044309 neuron spine 95 -0.5249207 -1.946215 0.0000063 0.0002236 0.0001806 1708 tags=34%, list=16%, signal=29% Actn1/Ncoa2/Pdlim4/Fmr1/Apba3/Myo5b/Myh10/Atp2b2/Arf4/Srgap2/Rgs14/Rhoa/Slc9a6/Slc1a1/Hnrnpk/Fbxo2/Cdc42/Ppp1ca/Strn/Igf2bp1/Comt/Psmc2/Nedd4/Arpc2/Snx1/Marcks/Usp50/Rac1/Capzb/Canx/Itgb1/P2rx3
GO:0043197 GO:0043197 dendritic spine 92 -0.5268110 -1.938385 0.0000075 0.0002506 0.0002025 1708 tags=34%, list=16%, signal=29% Actn1/Ncoa2/Pdlim4/Fmr1/Apba3/Myo5b/Myh10/Atp2b2/Arf4/Srgap2/Rgs14/Rhoa/Slc1a1/Hnrnpk/Fbxo2/Cdc42/Ppp1ca/Strn/Igf2bp1/Comt/Psmc2/Nedd4/Arpc2/Snx1/Marcks/Usp50/Rac1/Capzb/Canx/Itgb1/P2rx3
GO:0009295 GO:0009295 nucleoid 46 -0.6262179 -2.029148 0.0000254 0.0006698 0.0005411 1083 tags=28%, list=10%, signal=25% Tfam/Atp5b/Elac2/Dbt/Acadvl/Slc25a5/Lrpprc/Sod2/Shmt2/Hadhb/Hspa9/Vdac2/Polg
GO:0042645 GO:0042645 mitochondrial nucleoid 46 -0.6262179 -2.029148 0.0000254 0.0006698 0.0005411 1083 tags=28%, list=10%, signal=25% Tfam/Atp5b/Elac2/Dbt/Acadvl/Slc25a5/Lrpprc/Sod2/Shmt2/Hadhb/Hspa9/Vdac2/Polg
GO:0045121 GO:0045121 membrane raft 185 -0.4270887 -1.716076 0.0000264 0.0006698 0.0005411 1912 tags=27%, list=18%, signal=23% Ahnak/Ctsd/Hspd1/Park7/Slc2a1/Tpp1/Insr/Cblb/Pgk1/Anxa2/Slc9a3r1/Vcl/Hmox1/Atp2b2/Adcy3/Mapt/Dlg1/Bsg/Cxadr/Atp5b/Mapk1/Slc1a1/Coro1c/Flot1/Cd55/Lyn/Gnai3/Nos1/Sdcbp/Cr1l/Atp1b1/Ldlr/Nedd4/Emp2/Slc25a5/Eno1b/Ctnnb1/Capn2/Actb/Tubb5/Slc25a4/Atp5a1/Tuba1a/Itgb1/Vdac2/Cdh1/Gja1/Tuba1b/Dag1/P2rx3
GO:0008540 GO:0008540 proteasome regulatory particle, base subcomplex 12 -0.8571907 -2.017731 0.0000267 0.0006698 0.0005411 647 tags=75%, list=6%, signal=71% Psmc3/Psmd2/Psmc2/Psmc1/Psmc4/Psmd1/Psmd5/Psmd4/Psmc5
GO:0098590 GO:0098590 plasma membrane region 497 -0.3183143 -1.409822 0.0000873 0.0020205 0.0016323 2233 tags=28%, list=21%, signal=23% 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
GO:0042555 GO:0042555 MCM complex 11 -0.8226443 -1.881648 0.0005256 0.0085515 0.0069082 1305 tags=64%, list=12%, signal=56% Mcmbp/Mcm2/Mcm5/Mcm8/Mcm6/Mcm7/Mcm4
GO:0030126 GO:0030126 COPI vesicle coat 10 -0.8250158 -1.845418 0.0007731 0.0122468 0.0098934 879 tags=40%, list=8%, signal=37% Copb2/Copg1/Copa/Arcn1
GO:1905369 GO:1905369 endopeptidase complex 66 -0.5080234 -1.758149 0.0009589 0.0142984 0.0115507 1608 tags=38%, list=15%, signal=32% Psmd8/Psmc6/Ide/Ubr1/Psmd6/Pigs/Psmb6/Psmd11/Pigu/Hspb1/Rad23a/Psmc3/Gpaa1/Psmd2/Psmc2/Psmc1/Vcp/Psmc4/Psmd1/Psmd5/Psmb5/Ubqln1/Psmd4/Psmd3/Psmc5
GO:0101031 GO:0101031 chaperone complex 27 -0.6389046 -1.852008 0.0011305 0.0162032 0.0130895 1917 tags=52%, list=18%, signal=43% Hspb8/Psmg1/Psmg2/Ppp5c/Hsp90ab1/Cct8/Cct4/Cct5/Tcp1/Cct2/Cct3/Cdc37/Dnajb11/Sdf2l1
GO:0098686 GO:0098686 hippocampal mossy fiber to CA3 synapse 10 -0.8122051 -1.816763 0.0012835 0.0171707 0.0138711 375 tags=50%, list=4%, signal=48% Fmr1/Bace1/Ywhaz/Capzb/P2rx3
GO:0030027 GO:0030027 lamellipodium 110 -0.4237266 -1.591426 0.0020161 0.0245724 0.0198504 1614 tags=25%, list=15%, signal=22% Pdlim4/Actr2/Scyl3/Pkn2/Myh10/Spata13/Rdx/Stx3/Srgap2/Rhoa/Coro1b/Coro1c/Flot1/Carmil1/Stxbp2/Wasf2/Arpc2/Ilk/Ctnnb1/Actb/Rac1/Tmod3/Capzb/Actr3/Cttn/P4hb/Cdh1/Dag1
GO:0043034 GO:0043034 costamere 11 -0.7875952 -1.801479 0.0020842 0.0245805 0.0198569 374 tags=64%, list=4%, signal=61% Fxr1/Ahnak/Vcl/Ilk/Krt8/Actg1/Dag1
GO:0030659 GO:0030659 cytoplasmic vesicle membrane 344 -0.3179147 -1.357031 0.0024321 0.0271131 0.0219028 2416 tags=30%, list=23%, signal=24% Copb1/Abcc4/Lztr1/Wdr91/Vps4a/Htt/Snx17/Pip5k1c/Gosr2/Slc2a3/Rffl/Kdelr3/Eps15/Syngr2/Ptprs/Atp13a2/Ap1g1/Clta/Pi4ka/Pacsin2/Ankfy1/Tmed10/Vps36/Sar1a/Calm3/Lamp1/Ctsd/Snx21/Ap2a2/Vps28/Syt2/Tpcn2/Sparc/Scamp4/Actn1/Vps4b/Stx7/Sec24d/Rab11fip4/Appl2/Sec24b/Sun1/Mvb12a/Anxa2/H2-DMa/Scamp2/Litaf/Chmp1a/Slc15a4/Vti1b/Dlg1/Stx3/Rcc2/Bsg/Ehd1/Vac14/Shc1/Csf3r/Slc9a6/Snx5/Vps35/Chmp2b/Slc1a1/Coro1c/Copb2/Cmtm6/Synpr/Rap2c/Rab4a/Slc39a14/Tmbim1/Anxa7/Sec23b/Tmem175/Stxbp2/H2-DMb2/Kdelr2/Pld3/Appbp2/Dab2/Copg1/Ldlr/Snx4/Sppl2b/Tmem9/Snx1/H2-DMb1/Copa/Itm2b/Sec31a/Usp50/Ap2s1/H2-K1/Rac1/Tsg101/Snx2/Sec61a1/Ap2m1/Chmp7/Arcn1/Znrf2/Cltc
GO:0005771 GO:0005771 multivesicular body 33 -0.5788391 -1.766420 0.0026961 0.0295097 0.0238389 2307 tags=45%, list=22%, signal=36% Chmp5/Atp13a2/Acpp/Lamp1/H2-DMa/Rab11a/Chmp1a/Chmp2b/H2-DMb2/Tmem9/Bace1/Steap3/H2-Ab1/Chmp7/Gja1
GO:0098685 GO:0098685 Schaffer collateral - CA1 synapse 36 -0.5590635 -1.745447 0.0029422 0.0300209 0.0242519 1668 tags=39%, list=16%, signal=33% Abr/Fmr1/Myo5b/Ppp3r1/Akap12/Stx3/Tubb2b/Ctnnb1/Efnb2/Actb/Capzb/Itgb1/Actg1/P2rx3
GO:0030141 GO:0030141 secretory granule 154 -0.3723051 -1.455272 0.0030165 0.0302660 0.0244499 2289 tags=31%, list=21%, signal=25% Lrp1/Slc2a3/Pcsk1n/Ebag9/Tmed10/Acpp/Sod1/Lamp1/Pla2g10/Hspd1/Wfs1/Ap2a2/Syt2/Sparc/Actn1/Pdia3/Pomt1/Stx7/Sun1/Hgs/Csnk2a2/Slc30a5/Skil/Myh9/Stx3/Bsg/Atp6v1a/Cxadr/Fstl3/Akt2/Atp2c1/Tcp1/Rab4a/Cdc42/Smpd1/Anxa7/Stxbp2/Gnai3/Nos1/Chga/Cyp51/Gars/Arpc2/Dld/Calr/Itgb1/Ap2m1/Vdac2
GO:0017053 GO:0017053 transcription repressor complex 51 0.5244697 1.686785 0.0041467 0.0383049 0.0309440 1662 tags=31%, list=16%, signal=27% Rbbp8/Gps2/Hdac5/Hdgf/Lin52/Hmgb1/Mier1/Jun/Spen/Bhlhe41/Ccnd1/Gata1/C1d/Sp1/Prdm10/Relb
GO:1902555 GO:1902555 endoribonuclease complex 28 0.6067168 1.736683 0.0041995 0.0383049 0.0309440 1380 tags=32%, list=13%, signal=28% Ago1/Rpp25/Rpp38/Rpp30/Pop5/Tsen2/Tarbp2/Ago3/Prorp
GO:0009986 GO:0009986 cell surface 284 -0.3273217 -1.382978 0.0049475 0.0437998 0.0353830 1735 tags=23%, list=16%, signal=20% Sparc/Pdia3/Fgfr2/Insr/Hsp90ab1/Fcgrt/Tnfrsf11a/Ide/Anxa2/H2-DMa/Alppl2/Clstn1/B4galt1/Lrrc8a/Erp44/Pdgfra/Atp5o/Adgre5/Atpif1/Hnrnpm/Anxa4/Csf3r/Atp5b/Clic4/Nectin2/Slc1a1/Flot1/Cd55/Kiss1r/Tmem102/Septin2/Plau/Phb/Aimp1/Ephb6/Atp1b2/Adam15/Cr1l/Ldlr/Clptm1/Jam2/Emp2/Erp29/Arpc2/Bace1/Eno1b/Capn2/Eno1/Epcam/Acvr1b/Calr/H2-K1/Tspan8/Gsr/Tjp2/Hspa5/Atp5a1/Itgb1/H2-Ab1/Krt18/Plet1/P4hb/Cdh1/Pdia4/Dag1
GO:0046930 GO:0046930 pore complex 14 -0.6974504 -1.708034 0.0054999 0.0479846 0.0387636 474 tags=29%, list=4%, signal=27% Spg7/Slc25a5/Slc25a4/Vdac2 

sessionInfo()
## R version 4.1.3 (2022-03-10)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.6 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=it_IT.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=it_IT.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=it_IT.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=it_IT.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] stats4    stats     graphics  grDevices utils     datasets  methods  
## [8] base     
## 
## other attached packages:
##  [1] GOSemSim_2.20.0             enrichplot_1.14.2          
##  [3] org.Mm.eg.db_3.14.0         AnnotationDbi_1.56.2       
##  [5] clusterProfiler_4.2.2       data.table_1.14.6          
##  [7] vsn_3.62.0                  ggrepel_0.9.2              
##  [9] ggplot2_3.4.0               DESeq2_1.34.0              
## [11] SummarizedExperiment_1.24.0 Biobase_2.54.0             
## [13] MatrixGenerics_1.6.0        matrixStats_0.62.0         
## [15] GenomicRanges_1.46.1        GenomeInfoDb_1.30.1        
## [17] IRanges_2.28.0              S4Vectors_0.32.4           
## [19] BiocGenerics_0.40.0        
## 
## loaded via a namespace (and not attached):
##   [1] ggtree_3.2.1           fgsea_1.20.0           colorspace_2.0-3      
##   [4] qvalue_2.26.0          XVector_0.34.0         aplot_0.1.8           
##   [7] rstudioapi_0.14        farver_2.1.1           graphlayouts_0.8.3    
##  [10] affyio_1.64.0          bit64_4.0.5            scatterpie_0.1.8      
##  [13] fansi_1.0.3            codetools_0.2-18       splines_4.1.3         
##  [16] cachem_1.0.6           geneplotter_1.72.0     knitr_1.40            
##  [19] polyclip_1.10-4        jsonlite_1.8.3         annotate_1.72.0       
##  [22] GO.db_3.14.0           png_0.1-7              ggforce_0.4.1         
##  [25] BiocManager_1.30.22    compiler_4.1.3         httr_1.4.4            
##  [28] lazyeval_0.2.2         assertthat_0.2.1       Matrix_1.5-3          
##  [31] fastmap_1.1.0          limma_3.50.3           cli_3.4.1             
##  [34] tweenr_2.0.2           htmltools_0.5.3        tools_4.1.3           
##  [37] igraph_1.3.5           gtable_0.3.1           glue_1.6.2            
##  [40] GenomeInfoDbData_1.2.7 affy_1.72.0            reshape2_1.4.4        
##  [43] DO.db_2.9              dplyr_1.0.10           fastmatch_1.1-3       
##  [46] Rcpp_1.0.9             jquerylib_0.1.4        vctrs_0.5.1           
##  [49] Biostrings_2.62.0      nlme_3.1-155           ape_5.6-2             
##  [52] preprocessCore_1.56.0  ggraph_2.1.0           xfun_0.35             
##  [55] stringr_1.4.1          lifecycle_1.0.3        XML_3.99-0.12         
##  [58] DOSE_3.20.1            zlibbioc_1.40.0        MASS_7.3-55           
##  [61] scales_1.2.1           tidygraph_1.2.2        parallel_4.1.3        
##  [64] RColorBrewer_1.1-3     yaml_2.3.6             memoise_2.0.1         
##  [67] gridExtra_2.3          ggfun_0.0.8            downloader_0.4        
##  [70] yulab.utils_0.0.5      sass_0.4.2             stringi_1.7.8         
##  [73] RSQLite_2.2.18         highr_0.9              genefilter_1.76.0     
##  [76] tidytree_0.4.1         BiocParallel_1.28.3    rlang_1.0.6           
##  [79] pkgconfig_2.0.3        bitops_1.0-7           evaluate_0.18         
##  [82] lattice_0.20-45        purrr_0.3.5            labeling_0.4.2        
##  [85] treeio_1.18.1          patchwork_1.1.2        shadowtext_0.1.2      
##  [88] bit_4.0.5              tidyselect_1.2.0       plyr_1.8.8            
##  [91] magrittr_2.0.3         R6_2.5.1               generics_0.1.3        
##  [94] DelayedArray_0.20.0    DBI_1.1.3              pillar_1.8.1          
##  [97] withr_2.5.0            prettydoc_0.4.1        survival_3.2-13       
## [100] KEGGREST_1.34.0        RCurl_1.98-1.9         tibble_3.1.8          
## [103] crayon_1.5.2           utf8_1.2.2             rmarkdown_2.18        
## [106] viridis_0.6.2          locfit_1.5-9.6         grid_4.1.3            
## [109] blob_1.2.3             digest_0.6.30          xtable_1.8-4          
## [112] tidyr_1.2.1            gridGraphics_0.5-1     munsell_0.5.0         
## [115] ggplotify_0.1.0        viridisLite_0.4.1      bslib_0.4.1